26 results
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome ... Syndrome is a rare ... thiazide-sensitive sodium-chloride ... H+ secretion → Hypokalemia ... #nephrology #diagnosis
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Hypokalemia - Differential ... • HTN, High Aldosterone ... , Gitelman syndrom ... @priti899 #Hypokalemia ... potassium #low #nephrology
Algorithm for patients with hypokalemia on the basis of the potassium-to-creatinine ratio in the urine
Urine K+
patients with hypokalemia ... creatinine) • Cell shift ... , Gitelman syndrome ... #hypokalemia ... algorithm #diagnosis #nephrology
Causes of Hypernatremia - Differential Diagnosis Algorithm
Hypernatremia - Excess free water loss, Serum Sodium >145 mmol/L
High
Causes of Hypernatremia ... Diagnosis Algorithm Hypernatremia ... water loss, Serum Sodium ... >145 mmol/L High ... #Nephrology #Differential
Hypokalemia Differential Diagnosis Algorithm
Hypertensive:
 • High Al, Low R - Primary aldosteronism
 • High Al, High
Hypokalemia Differential ... Hypertensive: • High ... , Gitelman's syndrome ... #Hypokalemia # ... Diagnosis #Algorithm #nephrology
Drugs associated with hypokalemia and hypomagnesemia

Hypokalemia
- Shift from extracellular fluid to intracellular fluid compartment
  -
- Shift from extracellular ... - Insulin (high ... overdose) - Sodium ... renal Fanconi syndrome ... differential #diagnosis #nephrology
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
: SIADH, Renal Sodium ... diuresis can be high ... : Hypovolemia, Hypervolemia ... Cirrhosis, Nephrotic syndrome ... #nephrology
Hypernatremia - Differential Diagnosis Workup Algorithm

1) Check Urine Osmolality:
 > 600 mOsm/kg - Implies extrarenal mechanism
: > 600 mOsm/kg ... Hypervolemic: Conn syndrome ... , Cushing syndrome ... Workup #Algorithm #nephrology ... #sodium
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
Gitelman Syndrome ... thiazide-sensitive sodium ... cotransporter • Gitelman's ... thiazide-sensitive sodium ... #nephrology #management
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
Hypokalemia Evaluation ... Before evaluating hypokalemia ... urinary losses: • High ... , Gitelman syndrome ... differential #potassium #nephrology