33 results
Hypokalemia - Differential Diagnosis Algorithm

Transcellular Shift:
 • Alkalosis
 • ↑ beta-2 adrenergic simulation 
 • Erythropoiesis
Hypokalemia - Differential ... Transcellular Shift ... • Refeeding syndrome ... Transcellular shifts ... Diagnosis #Algorithm #nephrology
Localization of Renal Tubular Defects
Fanconi Syndrome: Proximal tubule
Bartter Syndrome: Thick ascending loop of Henle
Gitelman Syndrome: Distal
Defects Fanconi Syndrome ... tubule Bartter Syndrome ... #Localization #Nephron ... #Defects #Pathophysiology ... #Nephrology
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Pathophysiology ... delivery to distal nephron ... H+ secretion → Hypokalemia ... #Pathophysiology ... #nephrology #diagnosis
NSAIDS and their effects on the Kidney - Pathophysiology

Arachidonic Acid metabolites into alternative pathways that modify
on the Kidney - Pathophysiology ... distal component of Nephron ... hyporenin hypoaldo, hyperkalemic ... absorption in distal nephron ... KidneyDisease #nephrology
Hyperkalemia Treatment Options
Stabilize cardiac membrane:
 • IV Calcium (peaks 5-10 minutes)
Decrease potassium concentration:
 • IV Fluids
Shift
Hyperkalemia Treatment ... • IV Fluids Shift ... LouLectures #Hyperkalemia ... management #potassium #nephrology
Mechanisms of nephron damage in cardiorenal syndrome
 • Increased renal interstitial pressure
 • Hypoperfusion
 • Reduced
Mechanisms of nephron ... in cardiorenal syndrome ... #cardiorenal #syndrome ... #Mechanisms #pathophysiology ... #nephrology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
- Compartment syndrome ... or compartment syndrome ... Shift of extracellular ... per day until stable ... #nephrology
Drugs associated with hypokalemia and hypomagnesemia

Hypokalemia
- Shift from extracellular fluid to intracellular fluid compartment
  -
associated with hypokalemia ... hypomagnesemia Hypokalemia ... - Shift from extracellular ... renal Fanconi syndrome ... differential #diagnosis #nephrology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Hyperkalemia - Differential ... Suspicion for Hyperkalemia ... Intracellular Shift ... - Tumor lysis syndrome ... potassium #high #nephrology
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
iniury, Compartment syndrome ... Dermatomyositis) AKI - Pathophysiology ... Shift of extracellular ... per day until stable ... Dialysis for severe hyperkalemia