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differential causes nephrology management medications comparison treatment algorithm hypokalemia high pathophysiology classification druginduced low reactions rhabdomyolysis summary toxicology angiotensin binding
Key Characteristics of Old and New Potassium-Binding Agents - Dr. Edgar V. Lerma https://twitter.com/edgarvlermamd #Potassium #Binding #KBinders #Kayexelate
edgarvlermamd #Potassium ... #Binding #KBinders ... Kayexelate #Comparison #Table ... #Pharmacology # ... Patiromer #HyperKalemia
Veltassa (Patiromer) MECHANISM: Potassium Binder INDICATION: Treatment of Hyperkalemia FORMULATION: Powder for oral suspension DOSING: 8.4
) MECHANISM: Potassium ... from other oral drugs ... patiromer) is a potassium ... this from other drugs ... Pharmacology
Causes of Hyperkalemia - Differential Diagnosis Algorithm • Increased Intake • Reduced Excretion (IV potassium with
Causes of Hyperkalemia ... - Differential Diagnosis ... Excretion (IV potassium ... Transcellular Shift ... #Hyperkalemia
Mechanisms of Drug-Induced Hyperkalemia • Direct renin inhibitor (Aliskiren) • Renin release inhibition (NSAIDs, Beta-Blockers)
Mechanisms of Drug-Induced ... • Increased EC shift ... #differential #diagnosis ... pathophysiology #pharmacology ... #potassium #medications
Potassium Binders for Management of Hyperkalemia • SPS - Sodium polystyrene sulfonate • Patiromer (veltassa) •
Potassium Binders ... Management of Hyperkalemia ... #Hyperkalemia # ... treatment #pharmacology ... #table #comparison
Potassium-Binding Agents to Treat Hyperkalemia Sodium zirconium cyclosilicate (Lokelma): • Mechanism: Preferentially captures K in exchange for
Potassium-Binding ... of aspiration #Potassium ... #medications #pharmacology ... #table #comparison ... #binders
Hypokalemia - Differential Diagnosis Algorithm Transcellular Shift: • Alkalosis • ↑ beta-2 adrenergic simulation • Erythropoiesis
Hypokalemia - Differential ... Diagnosis Algorithm ... Transcellular Shift ... Transcellular shifts ... nephrology #low #potassium
Hyperkalemia: Diagnostic algorithm Decreased renal potassium excretion • Acute renal failure • Chronic renal failure • Drugs Increased
Hyperkalemia: Diagnostic ... Decreased renal potassium ... Increased potassium ... • Type 1 #Hyperkalemia ... #Diagnosis #algorithm
Causes of Hyperkalemia Hyperkalemia is caused by excess potassium intake, impaired potassium excretion, or transcellular shifts. The
caused by excess potassium ... intake, impaired potassium ... transcellular shifts ... adapt to excess potassium ... dysfunction is common #Diagnosis
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 Drugs that Impair Renal Potassium Excretion Decreased ENaC channel function: Amiloride, Triamterene, Pentamidine Decreased Aldosterone Synthesis: Heparin,
Drugs that Impair ... Renal Potassium ... happypillsrx/ #Hyperkalemia ... Pathophysiology #Pharmacology ... #Impaired #Potassium
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