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diagnosis differential hyperkalemia management nephrology blood pharmacology product reactions treatment algorithm anesthesia anesthesiology arthritis bradycardia checklist classification clinical comparison complexes
Digoxin Pharmacology and Pathophysiology 1) Na/K ATPase Pump - Digoxin works by directly binding to and inhibiting
intracellular calcium causes ... - Hyperkalemia ( ... high potassium levels ... (or low potassium ... Pathophysiology #cardiology
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
phlebotomy High ... : • Digoxin ... Intracellular Shift ... differential #diagnosis #causes ... #potassium #high
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
phlebotomy High ... : • Digoxin ... Intracellular Shift ... differential #diagnosis #causes ... #potassium #high
Causes of Hyperkalemia - Intercellular Shift - Differential Diagnosis Algorithm Transcellular Shift - Appropriate renal excretion (GFR,
Causes of Hyperkalemia ... Intercellular Shift ... , TTKG, distal flow ... • Cell Lysis (e.g ... -1 agonism • Digoxin
Hyperkalemia - Diagnosis and Management - GrepMed Handbook S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Calcineurin inhibitors, Digoxin ... heparinized tube) • ECG ... only if no clear cause ... acidosis) • Low ... Management #Treatment #potassium
Premature Ventricular Complexes (PVC's) - Summary Framework Why PVCs? Can be the first manifestation of cardiac
Hypomagnesemia • Hypokalemia ... Substances • Digoxin ... classified as: • Low ... percent PVCs/day • High ... #differential #cardiology
Hyperkalemia Management Pseudohyperkalemia: 1. Hemolyzed sample 2. Blood drawn from a site/line where potassium or TPN is
Hyperkalemia Management ... site/line where potassium ... minutes-hour) -Shift ... or dialysis • SLOW ... #high
Gout (Gouty Arthritis) - MSK Radiology Imaging Findings: • Eccentric soft-tissue densities surrounding the third proximal interphalangeal
Arthritis) - MSK Radiology ... commonly intermediate-low ... Case description ... common, so maintain high ... diagnosis #msk #rheumatology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
immature blasts and high ... WBC count cause ... , Elevated Cr, Low ... hydration - Hyperkalemia ... diagnosis #management #hematology
Lactated Ringers (LR) vs Normal Saline (NS) - Comparison Composition of LR: • Sodium 130 mEq/L •
130 mEq/L • Potassium ... Is Dangerous in Hyperkalemia ... transcellular shift ... • Saline Causes ... densa receives high
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