34 results
Hypokalemia - Differential Diagnosis Algorithm

Transcellular Shift:
 • Alkalosis
 • ↑ beta-2 adrenergic simulation 
 • Erythropoiesis
Transcellular Shift ... • Refeeding syndrome ... Thyrotoxicosis Medications ... • Discontinued diuretic ... nephrology #low #potassium
Causes of Hypokalemia
Transcellular Shifts:
 - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
Causes of Hypokalemia ... Transcellular Shifts ... plasma insulin (treatment ... Conn's, Liddle's), Drugs ... #Causes #differential
Hypokalemia Differential Diagnosis Algorithm

Low intake 
• poor oral intake 

Renal loss 
• Medication 
• Hypomagnesemia 
•
Renal loss • Medication ... Hypomagnesemia • Osmotic diuresis ... • Bartter's syndrome ... Transcellular shift ... Diagnosis #Algorithm #Causes
Drugs associated with hypokalemia and hypomagnesemia

Hypokalemia
- Shift from extracellular fluid to intracellular fluid compartment
  -
- Shift from extracellular ... - Insulin (high ... renal Fanconi syndrome ... #Medications #differential ... diagnosis #nephrology #Causes
Algorithm for patients with hypokalemia on the basis of the potassium-to-creatinine ratio in the urine
Urine K+
the basis of the potassium-to-creatinine ... creatinine) • Cell shift ... Urine Cl - Loop diuretics ... , Thiazide diuretics ... #urine #potassium
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
reactions Common Drugs ... • K sparing diuretics ... Intracellular Shift ... Medications 2. ... #potassium #high
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Hypokalemia - Differential ... • HTN, High Aldosterone ... Loop and thiazide diuretics ... Diagnosis #Algorithm #causes ... #potassium #low
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
Mechanisms of Drug-Induced ... Hyperkalemia ... • Increased EC shift ... pathophysiology #pharmacology ... #potassium #medications
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
reactions Common Drugs ... • K sparing diuretics ... Intracellular Shift ... Medications 2. ... #potassium #high
Causes of Hypomagnesemia
Redistribution:
 - IV glucose
 - Correction of diabetic ketoacidosis
 - IV hyperalimentation
 - Refeeding
Causes of Hypomagnesemia ... - Potassium depletion ... renal disease Drugs ... #differential #medications ... #drugs #pharmacology