43 results
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS
Laboratory TLS:
 • Uric
Classification of Tumor Lysis ... Syndrome (TLS) ... 8.0 mg/dL • Potassium ... Treatment of TLS ... #TumorLysis #Syndrome
Hypokalemia - Differential Diagnosis Algorithm

Transcellular Shift:
 • Alkalosis
 • ↑ beta-2 adrenergic simulation 
 • Erythropoiesis
Diagnosis Algorithm ... Transcellular Shift ... • Refeeding syndrome ... Transcellular shifts ... nephrology #low #potassium
Pathophysiology of Tumor Lysis Syndrome (TLS)
Tumor Cell Lysis
-> Release of DNA
 • Purines -> Hypoxanthine /
Pathophysiology of Tumor Lysis ... Syndrome (TLS) ... Tumor Cell Lysis ... • Hyperkalemia ... #TLS #Pathophysiology
Causes of Hypokalemia - Differential Diagnosis Algorithm
Increased Loss 
 - Increased GI Loss
 - Increased Urinary
Causes of Hypokalemia ... Transcellular Shift ... - Refeeding Syndrome ... #Hypokalemia ... #causes #potassium
Causes of Hyperkalemia - Differential Diagnosis Algorithm
 • Increased Intake
 • Reduced Excretion (IV potassium with
Causes of Hyperkalemia ... Differential Diagnosis Algorithm ... Excretion (IV potassium ... Transcellular Shift ... #Hyperkalemia
Hypokalemia Differential Diagnosis Algorithm

Low intake 
• poor oral intake 

Renal loss 
• Medication 
• Hypomagnesemia 
•
Diagnosis Algorithm ... • Gitelman's syndrome ... • Bartter's syndrome ... Transcellular shift ... Differential #Diagnosis #Algorithm
Tumor Lysis Syndrome - Workup and Management

Initial workup: BMP, Serum uric acid, LDH, Urine output, Consider
Tumor Lysis Syndrome ... ≥ 8 mg/dL • Potassium ... of the above Treatment ... of Clinical TLS ... MatthewHoMD #TLS
Tumor lysis syndrome refers to the constellation of metabolic disturbances that occurs when large numbers of
Tumor lysis syndrome ... hyperuricemia, #hyperkalemia ... hyperphosphatemia, #hypocalcemia ... #Presentation #TLS
Algorithm for patients with hypokalemia on the basis of the potassium-to-creatinine ratio in the urine
Urine K+
Algorithm for patients ... the basis of the potassium-to-creatinine ... creatinine) • Cell shift ... #urine #potassium ... #differential #algorithm
Hyperkalemia: Diagnostic algorithm
Decreased renal potassium excretion
 • Acute renal failure
 • Chronic renal failure
 • Drugs
Increased
Hyperkalemia: Diagnostic ... algorithm Decreased ... transfusion • Tumor lysis ... • Type 1 #Hyperkalemia ... #Diagnosis #algorithm