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diagnosis differential causes management hyperkalemia high gitelman intercellularshift k low oncology pathophysiology summary tumorlysis urine
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS Laboratory TLS: • Uric
Classification of Tumor Lysis ... Syndrome (TLS) ... 8.0 mg/dL • Potassium ... Treatment of TLS ... #TumorLysis #Syndrome
Hypokalemia - Differential Diagnosis Algorithm Transcellular Shift: • Alkalosis • ↑ beta-2 adrenergic simulation • Erythropoiesis
Diagnosis Algorithm ... Transcellular Shift ... • Refeeding syndrome ... #nephrology #low ... #potassium
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
• Recent IV potassium ... Intracellular Shift ... reaction - Tumor lysis ... syndrome - Rhabdomyolysis ... #high #nephrology
Causes of Hyperkalemia - Intercellular Shift - Differential Diagnosis Algorithm Transcellular Shift - Appropriate renal excretion (GFR,
Causes of Hyperkalemia ... Intercellular Shift ... Tumor Lysis Syndrome ... , rhabdomyolysis ... IntercellularShift #Nephrology
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
• Recent IV potassium ... Intracellular Shift ... reaction - Tumor lysis ... syndrome - Rhabdomyolysis ... #high #nephrology
Algorithm for patients with hypokalemia on the basis of the potassium-to-creatinine ratio in the urine Urine K+
Algorithm for patients ... creatinine) • Cell shift ... #urine #potassium ... #differential #algorithm ... #diagnosis #nephrology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Rhabdomyolysis - ... HIV, Influenza, TSS ... Shift of extracellular ... Monitor potassium ... #nephrology
Rhabdomyolysis - Differential Diagnosis and Management Summary Trauma: • Immobilization, Crush iniury, Compartment syndrome, Electrical injury Exertional: •
iniury, Compartment syndrome ... HIV, Influenza, TSS ... Shift of extracellular ... Monitor potassium ... Dialysis for severe hyperkalemia
Hyperkalemia - Diagnosis and Management - GrepMed Handbook S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Acidosis, Cell Lysis ... (TLS, rhabdo/crush ... acidosis), CK+LDH (lysis ... Redistribution Treatments ... #potassium #nephrology
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
(renal potassium ... • Seizures • Rhabdomyolysis ... Treatment - ... Supplement: • Potassium ... #diagnosis #nephrology
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