46 results
Pharmacology of diuretics

Acetazolamide, Loop diuretics, Thiazide‐like diuretics, MRA, Amiloride

Site of Action, Maximum Dose, Half-Life, Onset, Bioavailability,
Pharmacology of ... #Pharmacology # ... Table #HalfLife #Dosing ... Thiazide #CHF #Cardiology ... #Management
Renal Actions of Diuretics

#Diuretics #Sites #Action #Nephron #Pharmacology #Nephrology
Renal Actions of ... Diuretics #Diuretics ... Action #Nephron #Pharmacology ... #Nephrology
Hypokalemia - Differential Diagnosis Algorithm

Transcellular Shift:
 • Alkalosis
 • ↑ beta-2 adrenergic simulation 
 • Erythropoiesis
Transcellular Shift ... Medications Renal ... Losses Non-renal ... • Discontinued diuretic ... Diagnosis #Algorithm #nephrology
Flowchart to diuretic use in acute heart failure.

(A) Congestion with volume overload. 

(B) Treatment algorithm after
Flowchart to diuretic ... administration, once a day dosing ... #Diuretic #Diuresis ... #HeartFailure #Cardiology ... #Management
Causes of Hypokalemia
Transcellular Shifts:
 - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
Transcellular Shifts ... Villous adenoma Renal ... chewing tobacco, Renal ... , Osmotic diuresis ... differential #diagnosis #nephrology
Drugs associated with hypokalemia and hypomagnesemia

Hypokalemia
- Shift from extracellular fluid to intracellular fluid compartment
  -
Hypokalemia - Shift ... foscarnet - Diuretics ... and other loop diuretics ... pump inhibitor - Renal ... differential #diagnosis #nephrology
Hyperkalemia Treatment Options
Stabilize cardiac membrane:
 • IV Calcium (peaks 5-10 minutes)
Decrease potassium concentration:
 • IV Fluids
Shift
• IV Fluids Shift ... (if preserved renal ... function) - Loop diuretic ... #Hyperkalemia #management ... #potassium #nephrology
Causes of Hyponatremia - Differential Diagnosis Algorithm
Hypovolemia, UNa > 20: 
 • Renal losses, Diuretic excess,
UNa > 20: • Renal ... losses, Diuretic ... deficiency, Salt-losing ... Ketonuria, Osmotic diuresis ... Algorithm #Causes #nephrology
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Regulating Renal ... irrigation • Management ... #Renal #Excretion ... #Diuresis #Nephrology ... #Pharmacology #
Hypokalemia Differential Algorithm
Acidosis
 - RTA
 - Diarrhea
pH Normal 
 1. Decreased Mg 
 2. Intracellular Shift
Intracellular Shift ... Diuretics (discontinued ... Renal artery stenosis ... Causes #Workup #Nephrology