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diagnosis differential causes management sodium workup hypophosphatemia hypokalemia framework hypernatremia hypocalcemia pathophysiology table acuteinterstitialnephritis acutetubulointerstitialnephritis allergicinterstitialnephritis calcium corticosteroids decisionaid diuresis
Hypophosphatemia - Differential Diagnosis Algorithm • Decreased intake/absorption: Starvation, Alcoholism, Malabsorption, Phosphate binder use • Redistribution/
Malabsorption, Phosphate ... Redistribution/ Shift ... bone syndrome • Renal ... #causes #nephrology ... #phosphate
Hypokalemia - Differential Diagnosis Algorithm Transcellular Shift: • Alkalosis • ↑ beta-2 adrenergic simulation • Erythropoiesis
Transcellular Shift ... Medications Renal ... Losses Non-renal ... vomiting) • Low ... #nephrology #low
Workup for Hyperphosphatemia - Differential Diagnosis Framework Rule out spurious hyperphosphatemia: paraproteinemia, hyperlipidemia, hemolysis, hyperbilirubinemia, liposomal amphotericin
t-PA, heparin Acute ... Phosphate Load: ... Transcellular Shift ... CKD Increased Renal ... #nephrology
Hypophosphatemia - Differential Diagnosis Algorithm Appropriately Low Kidney Phosphate Excretion: • Decreased GI Absorption: Chronic Diarrhea, Antacids,
Differential Diagnosis Algorithm ... Appropriately Low ... Transcellular Shift ... Refeeding Syndrome, Acute ... #nephrology #phosphorus
Workup for Hypophosphatemia - Differential Diagnosis Framework Rule out spurious hypophosphatemia: paraproteinemia, acute leukemia Measure Urine Fractional Excretion
paraproteinemia, acute ... Transcellular Shift ... FEPO4 ≥ 5% - Renal ... • Normal or Low ... #nephrology
Hyponatremia Differential Diagnosis Algorithm - Utilizing Uric Acid ADH promotes Urea/uric acid excretion along with water
Hyponatremia Differential ... Diagnosis Algorithm ... High Uric Acid → renal ... #nephrology #sodium ... #low #uricacid
Hypernatremia Management Algorithm Acute vs Chronic Calculate Losses • Current water Deficit • Ongoing Free water Losses •
Hypernatremia Management ... Algorithm Acute ... Medicine @SCVMCMed #Hypernatremia ... #Management #Algorithm ... #treatment #nephrology
Hypocalcemia Workup - Differential Diagnosis Algorithm • Low Magnesium, High Magnesium - Functional Hypoparathyroidism • High
Differential Diagnosis Algorithm ... • Low Magnesium ... Hyperphosphatemia, Acute ... Differential #Diagnosis #Algorithm ... #nephrology #calcium
Hyponatremia Diagnosis Algorithm UOsm ≥ POsm - Vasopressin-Dependent • UNa < 20 mEq/L - Appropriate (↓ EABV)
Hyponatremia Diagnosis ... Algorithm UOsm ... Primary polydipsia, Low ... solute intake, Renal ... #causes #nephrology
Hyponatremia - Differential Diagnosis Algorithm ADH Independent: • Tea and Toast Syndrome, Beer Potomania - Low solute
Hyponatremia - Differential ... Diagnosis Algorithm ... Beer Potomania - Low ... • Renal Failure ... #causes #nephrology
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