59 results
Cold Urticaria
Prevalence - 0.05% in the population
Disease onset - Mostly 2nd to 4th decades of life
Causes
decades of life Causes ... vertigo Diagnostic tests ... - Ice cube test ... , TempTest test ... Urticaria #diagnosis #rheumatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
PT, aPTT(liver disease ... K), H. pylori test ... thyroid function test ... bypass), LFT (liver disease ... #Workup #hematology
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Initial screening test ... with more severe disease ... Used to monitor disease ... Summary #diagnosis #rheumatology ... #management
Whipple Disease (Tropheryma whipplei) - Diagnosis and Management 

Caused by: Tropheryma whipplei

Symptoms and Signs:
1. Migratory poly/oligoarthralgia
Whipple Disease ... Diagnosis and Management ... Caused by: ... positive T. whipplei tests ... positive T. whipplei test
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Causes of Anemia ... Liver Function Tests ... Liver Function Tests ... • Liver Disease ... #Hematology
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Causes of Bone/Joint ... in Sickle Cell Disease ... predispose to other orthopedic ... Pain #SickleCell #Disease ... #hematology
Hydroxychloroquine Serum Measurement in SLE
 • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
if < 200ng/mL Best ... suspected) • In case ... • Special cases ... Measurement #SLE #rheumatology ... levels #lupus #management
Adrenal Insufficiency - Diagnosis and Management Summary
Primary Adrenal Insufficiency:
Most Common Cause in the US: Autoimmune Adrenalitis
Other
Diagnosis and Management ... or metastatic disease ... , infiltrative diseases ... A STIM test can ... ACTH STIM TEST:
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
hallmark for the disease ... value is low, tests ... indirect antiglobulin tests ... leukocytosis with a left shift ... Diagnosis #Workup #Hematology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
pathognomonic laboratory tests ... Positive pathergy test ... is a skin prick test ... Syndrome #diagnosis #management ... signs #symptoms #rheumatology