1077 results
Oxygen-Hemoglobin Dissociation Curve

Left Shift (↓ O2 unloading to tissue), Left = Lower:
 • ↓ H+ (↑
Curve Left Shift ... Temperature Right Shift ... Dissociation #Curve #pathophysiology
Oxyhemoglobin Dissociation Curve 

Left Shift - decreased unloading of O2 at tissue level (i.e.  increased
Curve Left Shift ... Hypophosphatæmia Right Shift ... Dissociation #Curve #Pathophysiology ... #Left #Right #Shift
Hypokalemia - Differential Diagnosis Algorithm

Transcellular Shift:
 • Alkalosis
 • ↑ beta-2 adrenergic simulation 
 • Erythropoiesis
Transcellular Shift ... Transcellular shifts
Causes of Hypokalemia - Differential Diagnosis Algorithm
Increased Loss 
 - Increased GI Loss
 - Increased Urinary
Transcellular Shift ... potassium #low #pathophysiology
Conceptual Relationship between Volume Responsiveness and Volume Tolerance

Assessing for volume responsiveness would only tell you that
Causes of "Left Shift ... Tolerance #IVFluids #Shift ... #Differential #Pathophysiology
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
• Increased EC shift ... differential #diagnosis #pathophysiology
Pathogenesis and Pathophysiology of Diabetic Ketoacidosis (DKA)

DKA is a result of an absolute or relative insulin
Pathogenesis and Pathophysiology ... driven by insulin) shifts ... details of the pathophysiology ... #Pathophysiology
Pivot-Shift Test in ACL-deficient Knee

This patient has pathologic varus alignment across the knee and a chronic
Pivot-Shift Test ... dr.dold.md #Pivot #Shift
Causes of Hyperkalemia - Differential Diagnosis Algorithm
 • Increased Intake
 • Reduced Excretion (IV potassium with
Transcellular Shift
Diabetes Pathophysiology and Medication Targets

The ominous octet is one concept that summarizes the different pathophysiologic pathways
Diabetes Pathophysiology ... the different pathophysiologic ... #Diabetes #Pathophysiology