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diagnosis differential causes hyperkalemia management algorithm medications treatment acidosis aniongap druginduced gitelman heat heatstroke hypomagnesemia hypomg illness metabolic nongap pharmacology
Hyperkalemia: Diagnostic algorithm Decreased renal potassium excretion • Acute renal failure • Chronic renal failure • Drugs Increased
Hyperkalemia: Diagnostic ... Normal, Renin High ... hypoplasia Aldosterone high ... • Type 1 #Hyperkalemia ... Diagnosis #algorithm #nephrology
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
phlebotomy High ... reactions Common Drugs ... Intracellular Shift ... lysis syndrome - Rhabdomyolysis ... #high #nephrology
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
phlebotomy High ... reactions Common Drugs ... Intracellular Shift ... lysis syndrome - Rhabdomyolysis ... #high #nephrology
Algorithm for patients with hypokalemia on the basis of the potassium-to-creatinine ratio in the urine Urine K+
patients with hypokalemia ... the basis of the potassium-to-creatinine ... creatinine) • Cell shift ... #urine #potassium ... algorithm #diagnosis #nephrology
Drugs associated with hypokalemia and hypomagnesemia Hypokalemia - Shift from extracellular fluid to intracellular fluid compartment -
Drugs associated ... with hypokalemia ... - Shift from extracellular ... - Insulin (high ... differential #diagnosis #nephrology
Mechanisms of Drug-Induced Hyperkalemia • Direct renin inhibitor (Aliskiren) • Renin release inhibition (NSAIDs, Beta-Blockers)
Mechanisms of Drug-Induced ... Hyperkalemia ... • Increased EC shift ... differential #diagnosis #pathophysiology ... #pharmacology #potassium
Rhabdomyolysis - Differential Diagnosis and Management Summary Trauma: • Immobilization, Crush iniury, Compartment syndrome, Electrical injury Exertional: •
Drugs (Statins), ... Dermatomyositis) AKI - Pathophysiology ... Shift of extracellular ... Monitor potassium ... Dialysis for severe hyperkalemia
Causes of High-anion Gap and Non-anion Gap Metabolic Acidosis Causes of High-anion Gap Acidosis: • Lactic acidosis
Causes of High-anion ... Acidosis Causes of High-anion ... Drug-induced hyperkalemia ... Potassium-sparing ... diagnosis #causes #nephrology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Rhabdomyolysis - ... - Toxins - Drugs ... Shift of extracellular ... Monitor potassium ... causes #treatment #nephrology
Causes of Hyperkalemia Pseudohyperkalemia - Tourniquet use - Hemolysis (in vitro) - Leukocytosis - Thrombocytosis Intra- to extracellular
Causes of Hyperkalemia ... shift - Acidosis ... chemotherapy - Rhabdomyolysis ... Renal failure* - Drugs—potassium-sparing ... acidosis) #Hyperkalemia
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