61 results
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
• Increased EC shift ... #hyperkalemia #differential ... #diagnosis #pathophysiology ... #pharmacology # ... potassium #medications
Causes of Hypokalemia - Differential Diagnosis Algorithm
Increased Loss 
 - Increased GI Loss
 - Increased Urinary
Hypokalemia - Differential ... Transcellular Shift ... #Hypokalemia #Differential ... Algorithm #causes #potassium ... #low #pathophysiology
Hypokalemia - Differential Diagnosis Algorithm

Transcellular Shift:
 • Alkalosis
 • ↑ beta-2 adrenergic simulation 
 • Erythropoiesis
Hypokalemia - Differential ... Transcellular Shift ... Transcellular shifts ... #Hypokalemia #Differential ... nephrology #low #potassium
Causes of Hyperkalemia - Differential Diagnosis Algorithm
 • Increased Intake
 • Reduced Excretion (IV potassium with
Hyperkalemia - Differential ... Excretion (IV potassium ... Transcellular Shift ... Hyperkalemia #Nephrology #Differential
Hyperkalemia Treatment Options
Stabilize cardiac membrane:
 • IV Calcium (peaks 5-10 minutes)
Decrease potassium concentration:
 • IV Fluids
Shift
minutes) Decrease potassium ... • IV Fluids Shift ... potassium intracellularly ... #Hyperkalemia #management ... #potassium #nephrology
Hyperkalemia Hypokalemia - Differential Diagnosis and Management Algorithm

Dr Pravin Patel

#Hypokalemia #Hyperkalemia #potassium #differential #diagnosis #management
Hypokalemia - Differential ... Diagnosis and Management ... #Hyperkalemia #potassium ... #differential # ... diagnosis #management
Drugs that Impair Renal Potassium Excretion 

Decreased ENaC channel function: Amiloride, Triamterene, Pentamidine
Decreased Aldosterone Synthesis: Heparin,
that Impair Renal Potassium ... #Hyperkalemia #Pathophysiology ... #Pharmacology # ... Impaired #Potassium
Causes of Hyperkalemia

Hyperkalemia is caused by excess potassium intake, impaired potassium excretion, or transcellular shifts. The
caused by excess potassium ... intake, impaired potassium ... transcellular shifts ... adapt to excess potassium ... #Hyperkalemia #Differential
Oxyhemoglobin Dissociation Curve 

Left Shift - decreased unloading of O2 at tissue level (i.e.  increased
Curve Left Shift ... Hypophosphatæmia Right Shift ... Dissociation #Curve #Pathophysiology ... #Left #Right #Shift ... #Differential #
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
Rhabdomyolysis - Differential ... Diagnosis and Management ... Dermatomyositis) AKI - Pathophysiology ... Shift of extracellular ... Monitor potassium