12 results
Summary of Diuretic Agents 
Subclass, Drug, Mechanism of Action, Effects, Clinical Applications, Pharmacokinetics, Toxicities, Interaction
CARBONIC ANHYDRASE
Summary of Diuretic ... Agents Subclass, Drug ... Chlorthalidone POTASSIUM-SPARING ... #Medications #Pharmacology ... summary #table #nephrology
Drugs associated with hypokalemia and hypomagnesemia

Hypokalemia
- Shift from extracellular fluid to intracellular fluid compartment
  -
Drugs associated ... Hypokalemia - Shift ... hypomagnesemia #Medications ... differential #diagnosis #nephrology ... #Causes #hypomg
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
Mechanisms of Drug-Induced ... Angiotensin-converting enzyme (ACE ... • Increased EC shift ... pathophysiology #pharmacology ... #potassium #medications
ACEI or ARB Initiation
Hyperkalemia:
 - Review concurrent drugs
 - Moderate potassium Intake
 - Consider: diuretics, sodium
ACEI or ARB Initiation ... Review concurrent drugs ... - Moderate potassium ... - Review for causes ... Reassess concomitant medications
Here’s a review of the Renin-Angiotensin-Aldosterone system (RAAS)

This is a very common pathway that clinicians should
sodium, which causes ... RAAS inhibiting drug ... , ACEI, ARB, and ... diuretic, which ... ReninAngiotensinAldosteroneSystem #RAAS #Pharmacology
Causes of Hypomagnesemia
Redistribution:
 - IV glucose
 - Correction of diabetic ketoacidosis
 - IV hyperalimentation
 - Refeeding
Causes of Hypomagnesemia ... - Potassium depletion ... renal disease Drugs ... #differential #medications ... #drugs #pharmacology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
• K sparing diuretics ... • NSAIDs • ACE ... Intracellular Shift ... Medications 2. ... #nephrology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
• K sparing diuretics ... • NSAIDs • ACE ... Intracellular Shift ... Medications 2. ... #nephrology
Causes of High-anion Gap and Non-anion Gap Metabolic Acidosis
Causes of High-anion Gap Acidosis:
 • Lactic acidosis
Drugs II. ... Potassium-sparing ... diuretics (amiloride ... ACE-Is and ARBs ... #nephrology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Etiology: • Medications ... : K+, ACEi/ARBs, ... only if no clear cause ... Management #Treatment #potassium ... #nephrology #K