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diagnosis differential hyperkalemia hypokalemia druginduced high hypomagnesemia hypomg management treatment acidosis aldosterone angiotensin aniongap arb dysgeusia induced initiation k kdigo
Summary of Diuretic Agents Subclass, Drug, Mechanism of Action, Effects, Clinical Applications, Pharmacokinetics, Toxicities, Interaction CARBONIC ANHYDRASE
Summary of Diuretic ... Agents Subclass, Drug ... Chlorthalidone POTASSIUM-SPARING ... #Medications #Pharmacology ... summary #table #nephrology
Hypokalemia - Differential Diagnosis Algorithm Transcellular Shift: • Alkalosis • ↑ beta-2 adrenergic simulation • Erythropoiesis
Transcellular Shift ... Thyrotoxicosis Medications ... • Discontinued diuretic ... #nephrology #low ... #potassium
ACEI or ARB Initiation Hyperkalemia: - Review concurrent drugs - Moderate potassium Intake - Consider: diuretics, sodium
Review concurrent drugs ... - Moderate potassium ... - Review for causes ... Reassess concomitant medications ... Initiation #monitoring #algorithm
Drugs associated with hypokalemia and hypomagnesemia Hypokalemia - Shift from extracellular fluid to intracellular fluid compartment -
Drugs associated ... Hypokalemia - Shift ... hypomagnesemia #Medications ... differential #diagnosis #nephrology ... #Causes #hypomg
Mechanisms of Drug-Induced Hyperkalemia • Direct renin inhibitor (Aliskiren) • Renin release inhibition (NSAIDs, Beta-Blockers)
Mechanisms of Drug-Induced ... Angiotensin-converting enzyme (ACE ... • Increased EC shift ... pathophysiology #pharmacology ... #potassium #medications
Here’s a review of the Renin-Angiotensin-Aldosterone system (RAAS) This is a very common pathway that clinicians should
sodium, which causes ... RAAS inhibiting drug ... , ACEI, ARB, and ... diuretic, which ... ReninAngiotensinAldosteroneSystem #RAAS #Pharmacology
Causes of Hypomagnesemia Redistribution: - IV glucose - Correction of diabetic ketoacidosis - IV hyperalimentation - Refeeding
Causes of Hypomagnesemia ... - Potassium depletion ... renal disease Drugs ... #differential #medications ... #drugs #pharmacology
Drug Induced Kidney Injury • Pre-Renal: NSAIDS, CNI, ACEI/ARB, IL-2 therapy, Diuretics CAR-T therapy • Osmotic
Drug Induced Kidney ... : NSAIDS, CNI, ACEI ... IL-2 therapy, Diuretics ... differential #diagnosis #algorithm ... #nephrology #Medications
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
• K sparing diuretics ... • NSAIDs • ACE ... Intracellular Shift ... Medications 2. ... #nephrology
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
• K sparing diuretics ... • NSAIDs • ACE ... Intracellular Shift ... Medications 2. ... #nephrology
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