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differential hellp liver obstetrics oncology pregnancy table algorithm hepatitis thrombocytopenia apml chronic comatose defects differentiation disease enzymes hemolysis hepatorenal hrs
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP) Three syndromes in
the critically ill ... Elevated Liver tests ... Thrombocytopenia #TTPHUS ... #hematology #diagnosis ... #table #comparison
Thrombocytopenia and Pregnancy Three syndromes in the critically ill pregnant woman who presents with coagulation defects. 1) HELLP
Pregnancy Three syndromes ... Elevated Liver tests ... #HELLP #AFLP #Obstetrics ... #OBGyn #Hematology ... #Diagnosis #Comparison
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
necrosis HELLP Syndrome ... Disease #Pregnancy #hepatology ... obstetrics #hepatitis #comparison ... #differential #diagnosis ... #icp #HELLP #AFLP
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
clinical symptoms/signs ... box indicates all ... presence of metabolic syndrome ... ALP, alkaline phosphatase ... #Algorithm #Hepatology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
adults in the west ... Physical Exam/Signs ... Diagnosis: • ... aplasia • ITP ... workup #oncology #hematology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential Diagnosis ... vein: Budd-chiari syndrome ... source - Tests ... • Gilbert's syndrome ... #algorithm #hepatology
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Drug-associated, PCH, Evans Syndrome ... Defects: Sickle cell ... Laboratory Tests ... Blood Smear ↑ abnormal ... #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Thrombocytopenia (ITP ... number and appears abnormal ... types are abnormal ... low and appear abnormal ... #diagnosis #hematology
Inherited Qualitative Platelet Defects Bernard-Soulier Syndrome • Defect of adhesion due to a lack of GP Ib/IX/V
receptor] • Normal ... structure and cell ... Platelet #Defects #comparison ... #differential #diagnosis ... #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... • Induce blast cell ... 500 mg QD until normal ... organ dysfuxtion, ICU ... #management #hematology
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