11 results
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
Thrombocytopenia ... tests, Low Platelets ... AFLP #obstetrics #hematology ... #diagnosis #table ... #comparison
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
Thrombocytopenia ... Pregnancy Three syndromes ... tests, Low Platelets ... Obstetrics #OBGyn #Hematology ... #Diagnosis #Comparison
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
tests algorithm ... blood tests. ... blood tests, synthetic ... blood test derangement ... indicates all the tests
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential Diagnosis ... K), H. pylori test ... thyroid function test ... gastric bypass), LFT ... (liver disease)
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
- Differential Diagnosis ... test abnormalities ... NAFLD, Autoimmune, HELLP ... #hepatology #algorithm ... Transaminitis #LFTs
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Tests - Differential ... Diagnosis Algorithm ... Pregnancy - AFLP, HELLP ... Burak @kwburak #LFTs
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
, no necrosis HELLP ... Syndrome (Hemolysis ... features: Hemolysis, Thrombocytopenia ... obstetrics #hepatitis #comparison ... #differential #diagnosis
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
TTP, HUS, DIC, HELLP ... Drug-associated, PCH, Evans Syndrome ... Defects, Drugs, Liver ... Laboratory Tests ... #hematology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential Diagnosis ... vein: Budd-chiari syndrome ... • Pregnancy: HELLP ... extrahepatic source - Tests ... • Gilbert's syndrome
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
leukopenia, anemia, and thrombocytopenia ... • Liver function ... tests ↑ AST ↑ ALT ... #Diagnosis #Management ... #Hematology #Rheumatology