20 results
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Skin Conditions ... Scleroderma Thickened skin ... arthritis Discoid skin ... #pain #skin #rashes ... #differential #
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Sjögrens (15%) Skin ... Photosensitivity, Butterfly rash ... pain (20%) Renal disease ... erythematosus #signs ... #symptoms #diagnosis
Joint Disorders - Differential Diagnosis Algorithm
Monoarthritis
 • Septic
 • Crystalline
     - Gout
- Differential Diagnosis ... arthritis - with the skin ... Erythematosus (SLE ... should have other symptoms ... like “butterfly rash
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
erythematosus (SLE ... ) Signs / Symptoms ... Xeroderma (Dry skin ... Sjogrens #Syndrome #Pathophysiology ... #Symptoms
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... inflammation on skin ... Manifestations #pathophysiology ... #diagnosis #signs ... #symptoms #complications
Kawasaki Disease: Clinical Findings
Diagnostic Criteria - Fever and 4/5 of the following:
 • Conjunctivitis
 • Polymorphous
Kawasaki Disease ... • Polymorphous rash ... - Generalized Skin ... #Diagnosis #Pathophysiology ... #Signs #Symptoms
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Purpura, ischemic skin ... - Affects the skin ... Cryoglobulinemic Vasculitis - Skin ... glomerular ischemia - Skin ... Small Vessels: Skin
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
3rd Decade Skin ... permanent alopecia Differential ... Arthritis: • Joint ... Seizures • Strokes Skin ... Induced Lupus: • Symptoms
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Syndrome) is a skin ... inflamed or blistered skin ... with systemic disease ... development of skin ... deeper into the skin
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
response to local skin ... retinal damage) • Skin ... test (this is a skin ... ) Differential Diagnosis ... #signs #symptoms