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diagnosis differential dermatology rheumatology symptoms algorithm causes clinical dermatomyositis lupus photo skin sle syndrome vasculitis allergy anaphylaxis antimda5 antimda5dm antinxp2
Erythematous Rashes - THE ALGORITHMIC APPROACH Characterized by diffuse redness of the skin due to capillary congestion, erythematous
redness of the skin ... the Nikolsky sign ... staphylococcal scalded skin ... the Nikolsky sign ... fever or Nikolsky sign
Combination of Skin Findings and Arthritis in Pediatrics Patient - Differential Diagnosis Malar rash: • A
Combination of Skin ... on texture of skin ... migrans: • Target sign ... dermatology #arthritis #skin ... #differential #
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
chest (in a V-sign ... shoulders (in a shawl sign ... Inverse Gottron’s sign ... ulcerations • Skin ... 50% of cases • Skin
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Mucocutaneous Manifestations ... plugging -> Discoid Rash ... inflammation on skin ... Malar (butterfly) Rash ... pathophysiology #diagnosis #signs
Manifestations of Anaphylaxis by Body System Dermatologic/mucosal - Eyes: periorbital swelling/erythema, injected conjunctiva, tears - Oral mucosa:
Manifestations of ... tongue and lips - Skin ... : urticarial rash ... , morbilliform rash ... Diagnosis #Allergy #Signs
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 Maculopapular - Diagnostic Algorithm Pathophysiology: - Catch-all term with a wide range of potential pathophysiologic mechanisms and causative
Ill-appearing, vital sign ... New-onset fever with rash ... sulfa-drug - Skin ... #Dermatology #Rash ... Targetoid #Algorithm #Differential
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Sjögrens (15%) Skin ... Photosensitivity, Butterfly rash ... Polyneuropathy, Cranial nerve ... erythematosus #signs
Lymphocutaneous Sporotrichiosis Infection Landscaper w/ painless nodular rash of arm present for months wax and wane; diagnosis? Lymphocutaneous
painless nodular rash ... trauma leads to skin ... painless, no systemic signs ... biopsy preferred Differential
Characteristic clinical manifestations of Down syndrome Typical craniofacial appearance • Round face and flat
Characteristic clinical manifestations ... folds (a fold of skin ... Downs #Syndrome #PhysicalExam ... #Features #Signs ... #Manifestations
Heat Illnesses and Heat Stroke - Differential Diagnosis Framework Heat Cramps: • Muscle pain or spasm -
Heat Stroke - Differential ... fatigue Heat Rash ... blisters on the skin ... → Syncope • Signs ... Pale and sweaty skin
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