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diagnosis differential rheumatology dermatology sle causes erythematosus systemic vasculitis arthropathies arthropathy autoimmune classification color complications ddxof disorders erythematous febrile fever
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Sjögrens (15%) Skin ... Photosensitivity, Butterfly rash ... Demyelinating syndromes ... erythematosus #signs ... #symptoms #diagnosis
Joint Disorders - Differential Diagnosis Algorithm Monoarthritis • Septic • Crystalline - Gout
Diagnosis Algorithm ... arthritis - (Reiter’s syndrome ... arthritis - with the skin ... should have other symptoms ... like “butterfly rash
Erythematous Rashes - THE ALGORITHMIC APPROACH Characterized by diffuse redness of the skin due to capillary congestion, erythematous
redness of the skin ... staphylococcal scalded skin ... syndrome (SSS) ... , the differential ... erythematous rash
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings • Primary Sjögren's is a solitary process whereas secondary Sjögren's
RA) or systemic lupus ... / Symptoms: - ... Xeroderma (Dry skin ... #Pathophysiology ... #Symptoms
Maculopapular - Diagnostic Algorithm Pathophysiology: - Catch-all term with a wide range of potential pathophysiologic mechanisms and causative
Maculopapular - Diagnostic Algorithm ... Ill-appearing, vital sign ... sulfa-drug - Skin ... #Dermatology #Rash ... #Differential #
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
inflammation on skin ... Malar (butterfly) Rash ... Manifestations #pathophysiology ... #diagnosis #signs ... #symptoms #complications
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
) is a skin condition ... inflamed or blistered skin ... development of skin ... deeper into the skin ... small samples of skin
Papulosquamous Skin Rash - Differential Diagnosis Algorithm Erythrematous or violaceous papules & plaques with overlying scale •
Papulosquamous Skin ... Rash - Differential ... Diagnosis Algorithm ... Auspitz sign, Koebner's ... soles • Discoid Lupus
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Purpura, ischemic skin ... - Affects the skin ... Cryoglobulinemic Vasculitis - Skin ... glomerular ischemia - Skin ... Small Vessels: Skin
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
evidence of (fatigue, rash ... 3rd Decade Skin ... permanent alopecia Differential ... Seizures • Strokes Skin ... : • Symptoms limited
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