60 results
Generalized Hyperpigmentation Differentials
Use the Mnemonic "no skin SPARED"

Images from dermnet.nz and merckmanuals

Mnemonic from https://www.medscape.com/slideshow/dermatology-mnemonics-6011359#5 #diagnosis #differential
the Mnemonic "no skin ... dermatology-mnemonics-6011359#5 #diagnosis ... #differential # ... symptoms #signs ... #dermatology #skin
Leg Pain - Differential Diagnosis Framework

Bone/Joint Causes of Leg Pain:
 • Fracture
 • Arthritis
 • Gout/pseudogout
Diagnosis Framework ... thrombophlebitis Skin ... band syndrome • Shin ... Brittle nails - Skin ... skin • Inflammation
Hypothyroidism – symptoms and signs.

Symptoms: 
Tiredness/malaise, 
Weight gain,
Anorexia,
Cold intolerance, 
Poor memory,
Change in appearance, 
Depression, 
Poor libido,
Symptoms: Tiredness ... , Dry coarse skin ... Goitre), Dry skin ... #Diagnosis #PhysicalExam ... #Endocrinology
Erythroderma - Diagnostic Algorithm. Pathophysiology: 1) Extensive cutaneous capillary dilation, results in widespread exfoliation of the
Erythroderma - Diagnostic ... Pathophysiology: ... of germinative skin ... Basophils/Histamine 4) Skin-homing ... Nikolsky #Algorithm #Differential
Anaphylaxis: Signs and Symptoms
Anaphylaxis: when any egg of three conditions is met:
1. Acute onset of skin/mucosal
Acute onset of skin ... >2 of: • skin ... /mucosal symptoms ... #Anaphylaxis #pathophysiology ... #immunology #diagnosis
Hypothyroidism and Hyperthyroidism - Symptoms and Signs
Hypothyroidism:
 - General - From asymptomatic to myxedema coma, “Like
Menorrhagia - Skin ... • Skin is ... amenorrhea - Skin ... • Warm, moist skin ... #endocrinology
Cushing Syndrome - Signs and Symptoms
Generalized: Weight gain, Slow healing of cuts, Increased risk of infections,
Syndrome - Signs and Symptoms ... Muscular: Weakness Skin ... Syndrome #Signs #Symptoms ... #diagnosis #endocrinology
Differential Diagnosis and Evaluation of Hyponatremia:
1) Identification of onset (acute vs. chronic)
2) Presence of symptoms (HA,
Differential Diagnosis ... 2) Presence of symptoms ... status (edema, JVD, skin ... drug history #Diagnosis ... Pseudohyponatremia #Differential
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
lipolysis Signs/Symptoms ... tunnel, OSA, Incr skin ... #FeedbackLoop #endocrinology ... #pathophysiology
CREST Syndrome: Pathogenesis and Clinical Findings

CALCINOSIS (BB-sized, hard nodules in fingers)
RAYNAUD'S Phenomenon
ESOPHAGEAL DYSMOTILITY
SCLERODACTYLY (thickening and tightening
tightening of skin ... CREST #Syndrome #Pathophysiology ... #Diagnosis #Signs ... #Symptoms