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diagnosis differential rheumatology dermatology sle algorithm causes erythematosus joint management skin syndrome systemic vasculitis arthritis arthropathies arthropathy autoimmune behcet biliary
Sarcoidosis Non-caseating granulomas (Composed of T-helper & inflammatory cells) Clinical: • Disease fatal in 10% of
neuropathies • Skin ... Subcutaneous nodules, lupus ... dysrhythmias • Ophthalmologic ... #Diagnosis #Symptoms ... #Signs #Pulmonary
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Skin Conditions ... Scleroderma Thickened skin ... arthritis Discoid skin ... #joint #pain #skin ... #rashes #differential
Combination of Skin Findings and Arthritis in Pediatrics Patient - Differential Diagnosis Malar rash: • A
Combination of Skin ... on texture of skin ... migrans: • Target sign ... dermatology #arthritis #skin ... #differential #
Common organ involvements and symptoms in Sarcoidosis Lung 89-99% - Cough, dyspnoea, wheezing and stridor Skin 16-32% -
in Sarcoidosis ... wheezing and stridor Skin ... 16-32% - Lupus ... and syncope #Sarcoidosis ... #diagnosis #signs
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
plugging -> Discoid Rash ... inflammation on skin ... Malar (butterfly) Rash ... pathophysiology #diagnosis #signs ... #symptoms #complications
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Features of Systemic Lupus ... Sjögrens (15%) Skin ... Photosensitivity, Butterfly rash ... erythematosus #signs ... #symptoms #diagnosis
Joint Disorders - Differential Diagnosis Algorithm Monoarthritis • Septic • Crystalline - Gout
Joint Disorders - Differential ... arthritis - with the skin ... with Systemic Lupus ... should have other symptoms ... like “butterfly rash
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Syndrome) is a skin ... inflamed or blistered skin ... development of skin ... deeper into the skin ... small samples of skin
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Self-limiting, chronic but stable ... nodes: 13-15%, skin ... (16-32%): lupus ... Diagnosis #Management #Signs ... #Symptoms
Papulosquamous Skin Rash - Differential Diagnosis Algorithm Erythrematous or violaceous papules & plaques with overlying scale •
Papulosquamous Skin ... Rash - Differential ... Auspitz sign, Koebner's ... soles • Discoid Lupus ... #dermatology #Differential
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