25 results
Compelling and Possible Contraindications to Antihypertensive Drugs
Diuretics (thiazides)
 - Gout
 - Metabolic syndrome, Glucose intolerance, Pregnancy,
Antihypertensive Drugs Diuretics ... potential Ca2+ channel ... failure Ca2+ channel ... failure - Co-medication ... contraindications #table
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
• Mechanism: Exchanges ... nonspecifically binds ... #medications #pharmacology ... #table #comparison ... #binders
Hypomagnesemia - Etiologies by Mechanism

Decreased GI Uptake 
 - Poor dietary intake (particularly common in alcoholics)
Renal Loses - Medications ... abnormalities - Hypercalcemia ... - Hypokalemia ... - Osmotic diuresis ... Low #Magnesium #Table
Algorithm for Management of Acute and Chronic Hyperkalemia
Acute Hyperkalemia:
 - IV calcium (10 mL of 10%)
Algorithm for Management ... - Consider K+ binders ... ) - Effective diuretic ... bicarbonate - Consider binders ... #Algorithm #Management
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Hyponatremia • Hypercalcemia ... Renal Epithelial Channels ... Nonspecific Cation Channel ... #Pharmacology #Medications ... #Table
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Hyperkalemia - Diagnosis ... Etiology: • Medications ... Elimination (see Table ... STOP offending medications ... K-Binding Resins - Exchanges
Hyperkalemia shortens repolarization; changes in the T wave provide the earliest clues to hyperpotassemia.
 - At
Hyperkalemia shortens ... repolarization; changes ... #Diagnosis #Hyperkalemia ... #EKG #ECG #Changes ... #Progression #Table
Hypokalemia - Differential Diagnosis Algorithm

Transcellular Shift:
 • Alkalosis
 • ↑ beta-2 adrenergic simulation 
 • Erythropoiesis
Hypokalemia - Differential ... Diagnosis Algorithm ... Thyrotoxicosis Medications ... • Discontinued diuretic ... MatthewHoMD #Hypokalemia
Hypokalemia Differential Diagnosis Algorithm

Low intake 
• poor oral intake 

Renal loss 
• Medication 
• Hypomagnesemia 
•
Hypokalemia Differential ... Diagnosis Algorithm ... Renal loss • Medication ... Hypomagnesemia • Osmotic diuresis ... amzn.to/2LmUODZ #Hypokalemia
Intern Pocket Cards - Inpatient Blood Pressure Management Guide
ß-blockers:
 • Metoprolol, Carvedilol, Labetalol
 • Bradycardia, heart
Valsartan • AKI, hyperkalemia ... inhibitor use Calcium Channel ... , heart block Diuretics ... BloodPressure #medications ... #pharmacology #table