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Sjogren Syndrome - Signs, Symptoms and Diagnosis

#Sjogren #Syndrome #Signs #Symptoms #Diagnosis #rheumatology
Sjogren Syndrome ... and Diagnosis #Sjogren
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
Primary Sjogren’ ... ) #Primary #Sjogrens
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... enlargement Sjogren's ... or 3rd line #Sjogrens
Raynaud Phenomenon Differential Diagnosis:

Rheumatologic

 - MCC systemic sclerosis, RA, SLE, Sjogren syndrome, Antisynthetase syndrome, MCTD
Heme

 -
sclerosis, RA, SLE, Sjogren
Dysphagia - Differential Diagnosis Algorithm

Oropharyngeal Dysphagia 
Esophageal Dysphagia 
 • Upper 2/3 (striated muscle): stroke, NMJ
atrophy, SLE, Sjogren
Connective tissue disease-associated interstitial lung diseases

LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
PSS: Sjogren syndrome
Demyelinating Diseases - Differential Diagnosis
 • Inflammatory: MS, ADEM, NMO, Paraneoplastic, Sjogren's, Polyarteritis nodosa, SLE
 •
Paraneoplastic, Sjogren's
Causes of Pericardial Effusion - Differential Diagnosis
Infectious:
 • Viral: Enterovirus, Herpesvirus, Adenovirus, Parvovirus
 • Bacterial: Mycobacterium
Rheumatoid Arthritis, Sjogren
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
neonatal lupus and Sjogren ... Associated with Sjogren
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Anticoagulant (LAC) • Sjogren