21 results
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
Acquired von Willebrand ... Syndrome - Diagnosis ... and Management ... adsorption onto cancer ... #treatment #hematology
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... Associated with skin ... severe disease Treatment ... Summary #diagnosis #rheumatology ... #management
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... hematologic: Acute blood ... Rebound effect from treatment ... Malignancy: Metastatic cancer ... Diagnosis #Algorithm #hematology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
purpuric macules • Erythematous ... • Ulcerated, erythematous ... • Goodpasture syndrome ... vasculitis (inflamed blood ... rash #diagnosis #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... thrombosis and/or blood-brain ... CNS #neurology #rheumatology ... cerebritis #diagnosis #management ... #treatment
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
- Underlying cancer ... - Hematologic cancer ... neutrophils in the blood ... Treatment: - Systemic ... #diagnosis #dermatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
the secondary or acquired ... Systemic lupus erythematosus ... Treatment: • Corticosteroids ... #Diagnosis #Management ... #Hematology #Rheumatology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
just beneath the skin ... factor (GCSF) treatments ... marrow studies Treatment ... Immunosuppressive treatment ... #diagnosis #hematology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Lymphoma or other cancers ... gastric and breast cancer ... severe community-acquired ... : • Nephrotic syndrome ... hypogammaglobulinemia #immunology #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Phagocytosis of blood ... Purtilo (XLP) Acquired ... B-LNH), solid cancers ... Lymphohistiocytosis #diagnosis #management ... #rheumatology