50 results
Features of a Sickle Cell Crisis 
Sickle-cell disease - an autosomal recessive blood disorder.
Characterized by red
a Sickle Cell Crisis ... Crises can be precipitated ... The underlying pathophysiology ... 4 different mechanism ... of the baseline anaemia
Oxyhemoglobin Dissociation Curve 

Left Shift - decreased unloading of O2 at tissue level (i.e.  increased
• chronic anæmia ... - Sickle cell anemia ... Dissociation #Curve #Pathophysiology ... #Differential #Causes ... #Diagnosis
High Output Heart Failure - Pathophysiology and Differential Diagnosis
Obesity - Systemic Vasodilation, Vasoactive Adipokines
Arteriovenous Fistula -
Heart Failure - Pathophysiology ... and Differential Diagnosis ... Metabolism Severe Anemia ... #Differential #Diagnosis ... #cardiology #causes
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential Diagnosis ... l MD SOAP) - Risks ... practices that could cause ... changes), high MCV anemia ... #Differential #Diagnosis
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Syndrome (MD) - Diagnosis ... old, ~10,000 new cases ... diagnosed annually ... cytopenias (usually anemia ... risk-stratification • Risks
Serotonin-Norepinephrine Reuptake Inhibitors(SNRIs): Mechanisms and Side Effects

Withdrawal: Dizziness, Diarrhea, Insomnia, Nausea, Vomiting
Serotonin Syndrome - Potentially Life
Inhibitors(SNRIs): Mechanisms ... Diarrhea, Insomnia, Nausea ... gain Incr NE: Nausea ... SerotoninNorepinephrine #Inhibitors #Pathophysiology ... SideEffects #Psychiatry #Diagnosis
Anaplasma Infection - Anaplasma phagocytophilum
Pathophysiology: 
 • Obligate, intracellular bacteria
 • Transmitted via blacklegged tick —
phagocytophilum Pathophysiology ... is rare (< 10% cases ... ), cough (30% cases ... immature forms) • Anemia ... Anaplasma #Infection #diagnosis
Selective Serotonin Reuptake Inhibitors: Mechanisms and Side Effects
 • Serotonin Syndrome:
   - Autonomic Hyperactivity:
Reuptake Inhibitors: Mechanisms ... Dizziness - Nausea ... Serotonin #Inhibitors #Pathophysiology ... SideEffects #Psychiatry #Diagnosis
Rheumatoid arthritis (RA): Extra-articular manifestations
Skin: 
 • Inflammation of skin (esp. over areas of stress) forms
reticularis Blood: Anemia ... inflammation tends to cause ... pulmonary fibrosis (mechanism ... RheumatoidArthritis #RA #pathophysiology ... signs #symptoms #diagnosis
Causes of B12 deficiency. 

This great diagram shows normal absorption and outlines most possible causes. At
Causes of B12 deficiency ... most possible causes ... rest involve some mechanism ... #Differential #Causes ... #Diagnosis #Pathophysiology