19 results
Acute promyelocytic leukemia (blood). Typical morphologic features are bilobed ("butterfly") nuclei with dispersed chromatin, subtle to
Acute promyelocytic ... leukemia (blood ... features in most cases ... APML #Pathology #Hematology ... #Clinical #Smear
Hypersegmented neutrophil in a case of acute myeloid leukemia.

Dysplastic neutrophils are typically hypolobated but can be
neutrophil in a case ... of acute myeloid ... leukemia. ... AML #Clinical #Hematology ... #Pathology #Smear
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
Causes of Diffuse ... Fatigue • Acute ... Lymphoblastic Leukemia ... Diagnosis #Algorithm #Causes ... #Hematology #Oncology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
, APML, CLL Acute ... smear or on bone ... -> AML: Blast crises ... • Peripheral smear ... #Hematology #Oncology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
old, ~10,000 new cases ... transformation to acute ... leukemia Management ... #treatment #hematology ... #oncology
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
the total white blood ... translocation • Acute ... thrombocythemia • Acute ... Chickenpox Other Causes ... #hematology #basophils
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
Diagnosis Algorithm Blood ... Loss • Acute ... Normochromic RBCs on Smear ... Diagnosis #Algorithm #Causes ... #Hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
• Peripheral smear ... Lymphocytosis: Absolute blood ... ’s lymphoma or acute ... diagnosis #workup #oncology ... #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Chronic Lymphocytic Leukemia ... • Most common leukemia ... • Peripheral smear ... #oncology #hematology ... hemeonc #diagnosis #management
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
malignancy (Especially acute ... promyelocytic leukemia ... ABO incompatible blood ... • Peripheral smear ... #hematology