36 results
ANCA Vasculitis - GPA, MPA, Eosinophilic GPA

doi:10.1038/s41572-020-0204-y

#ANCA #Vasculitis #GPA #MPA #Eosinophilic #rheumatology #diagnosis #comparison #table
ANCA Vasculitis ... s41572-020-0204-y #ANCA ... #Vasculitis #GPA ... #Eosinophilic #rheumatology ... #diagnosis #comparison
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
ANA (Antinuclear ... Systemic lupus erythematosus ... Jcortesizaguirr #ANA ... Antineutrophil #antibodies #diagnosis ... #rheumatology #
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
often causes arthritis ... branches • GCA ... purpura: strong sign ... LFT • ESR • ANA ... #rheumatology #
ANCA-Associated Vasculitis
A group of necrotizing, small-vessel vasculitis without immune complex deposition. Complement levels are normal due
ANCA-Associated ... Hydralazine-induced ANCA ... @AnnKumfer #ANCA ... MPO #PR3 #Diagnosis ... #Rheumatology
Aortitis - Differential Diagnosis Framework
Non-Infectious Aortitis:
 • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
- Differential Diagnosis ... Cell Arteritis (GCA ... Nodosa (PAN), ANCA ... Systemic lupus erythematosus ... #rheumatology
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
pathophysiologic causes ... Negative IF): • PR3-ANCA ... (C-ANCA): GPA > ... > eGPA • MPO-ANCA ... (P-ANCA): eGPA,
ANCA-Associated Vasculitis
There are many definitions, but most come down to the presence of granulomas (pathologically or
ANCA-Associated ... polyangiitis (GPA ... StanfordChiefs #ANCA ... #diagnosis #algorithm ... #rheumatology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
purpura: Strong sign ... CRP GCA (Giant ... ischemia • Skin: Erythematous ... often causes arthritis ... #Rheumatology
Classification of Vasculitis 
Vasculitis of large vessels 
 - Arteritis temporalis (giant-cell arteritis) 
 - Takayasu
small vessels - ANCA-associated ... systemic lupus erythematosus ... #Vessels #Diagnosis ... #Rheumatology # ... Diagnosis
Vasculitis Involving the Skin - Differential Diagnosis Framework

Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis
Secondary: CTD: SLE, RA
- Differential Diagnosis ... • ANCA Associated ... polyangiitis - EGPA - GPA ... #dermatology #rheumatology ... #differential #diagnosis