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diagnosis differential acute aki hematuria instructions kidneyinjury nephritis proteinuria workup ain atlas biopsy blood clinical dipstick examination glomerular glucosuria granular
Granular & “Muddy Brown” Casts on Urine Microscopy A. Finely granular cast B. slightly coarser granular cast
“Muddy Brown” Casts ... on Urine Microscopy ... #Urine #Microscopy ... #Clinical #Nephrology ... #Sediment
Atlas of Urine Microscopy Findings • Epithelial cells - Normal • Renal tubular cells - Acute
Atlas of Urine Microscopy ... • Red cell casts ... • White cell casts ... key #diagnosis #nephrology ... #casts
Causes of Proteinuria - Differential Diagnosis Algorithm Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
sediment - WBC/ ... RBC casts ... polyangiitis (GPA) / microscopic ... sediment ... #Proteinuria #Nephrology
Urine Microscopy - Urinary Sediment Examination Instructions Preparation of the urine for microscopic examination: • Clean catch
Urine Microscopy ... up by cells or casts ... Ill stain) and crystals ... protein matrix of casts ... Instructions #steps #checklist
Urine Microscopy Instructions 1) Spin fresh urine sample (10-15mL) in a centrifuge for 3-5 minutes - Don't
Urine Microscopy ... 1) Spin fresh urine ... the remaining sediment ... under lower power (casts ... #nephrology #diagnosis
Hematuria - Differential Diagnosis Framework Gross Hematuria: Red/Dark urine • 1ml blood/liter urine can induce color change
sediment Microscopic ... sediment by microscopy ... hematuria: - RBC casts ... microscopic and ... #urology #nephrology
Algorithmic Approach to Acute Interstitial Nephritis When to suspect AIN? (not sensitive) • AKI, AKD, rapidly progressive
sterile pyuria, WBC casts ... eosinophiluria, microscopic ... proteinuria, granular casts ... /RTE; blend sediment ... #nephrology #diagnosis
Causes of Hematuria - Differential Diagnosis Algorithm Red blood cells on urine microscopy. Must exclude false positives
Differential Diagnosis Algorithm ... blood cells on urine ... microscopy. ... RBCs and/or RBC casts ... with polyangiitis/microscopic
Simplified Approach to Acute Kidney Injury (AKI) 1) IS THIS AN EMERGENCY? Is there a dialysis indication
PROBLEM ~80% of AKI cases ... IMPROVEMENT If the urine ... Assess UA w/ microscopy ... for WBCs, RBCs, casts ... , crystals, protein
Urinalysis & Urine Sodium Theophilus Protospatharius, a seventh-century physician who wrote the first manuscript focused exclusively
sediment and color ... Microscopic exam ... • Crystals ... • Urinary casts ... #UNa #casts #glucosuria
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