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diagnosis vasculitis differential antibodies classification diseases algorithm ana antinuclear acr2021 antibody antineutrophil arthritis associated associations autoantibodies canca causes cryoglobulinemia cryoglobulins
ANCA-Associated Vasculitis A group of necrotizing, small-vessel vasculitis without immune complex deposition. Complement levels are normal due
ANCA-Associated ... polyangiitis (GPA), microscopic ... - C-ANCA pattern ... involvement - PR3>MPO Microscopic ... #Diagnosis #Rheumatology
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
Antibody) and ANCA ... Vasculitis: • Microscopic ... 80-90%) > MPO - ANCA ... MPO: 75-80% - ANCA ... antibodies #diagnosis #rheumatology
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
Disease Associations ANA ... Graves' disease c-ANCA ... granulomatosis p-ANCA ... Microscopic polyangiitis ... diagnosis #table #rheumatology
Granulomatosis with Polyangiitis (GPA) and Microscopic Polyangiitis (MPA) - ANCA Vasculitis Management Algorithm - ACR/VF 2021
Polyangiitis (GPA) and Microscopic ... Polyangiitis (MPA) - ANCA ... Polyangiitis #GPA #Microscopic ... Polyangiitis #MPA #ANCA ... Guidelines #algorithm #rheumatology
ANCA-Associated Vasculitis There are many definitions, but most come down to the presence of granulomas (pathologically or
ANCA-Associated ... inflammation: • Microscopic ... StanfordChiefs #ANCA ... diagnosis #algorithm #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Associated - ANCA ... proteinase 3 (PR3-ANCA ... ): • Microscopic ... Dx: GPA, EGPA, microscopic ... differential #diagnosis #rheumatology
Vasculitis Involving the Skin - Differential Diagnosis Framework Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis Secondary: CTD: SLE, RA
Vasculitis • ANCA ... Associated: - Microscopic ... #dermatology #rheumatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
) ANA or Anti-NucIear ... Using fluorescence microscopy ... • +ANA can be seen ... The higher the ANA ... #patterns #rheumatology
Classification of Vasculitis Vasculitis of large vessels - Arteritis temporalis (giant-cell arteritis) - Takayasu
small vessels - ANCA-associated ... granulomatosis - microscopic ... Vessels #Diagnosis #Rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Pauci Immune (ANCA ... )): Microscopic ... No Granulomas (ANCA ... (-Granulomas) ANCA ... Differential #Diagnosis #Rheumatology
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