21 results
diagnosis differential antibodies classification erythematosus lupus sle symptoms syndrome ana antinuclear autoantibodies dermatology disease management antibody antineutrophil aortitis arthritis associated
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
antibodies) • Systemic ... drug-induced SLE) • Systemic ... Vasculitis: • ... Microscopic polyangiitis ... antibodies #diagnosis #rheumatology
ANCA-Associated Vasculitis A group of necrotizing, small-vessel vasculitis without immune complex deposition. Complement levels are normal due
ANCA-Associated ... polyangiitis (GPA), microscopic ... involvement - PR3>MPO Microscopic ... PR3 Anti-GBM disease ... PR3 #Diagnosis #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
): • Microscopic ... Vasculitis: + MPO-ANCA ... purpura: strong sign ... Dx: GPA, EGPA, microscopic ... differential #diagnosis #rheumatology
Classification of Vasculitis Vasculitis of large vessels - Arteritis temporalis (giant-cell arteritis) - Takayasu
central nervous system ... small vessels - ANCA-associated ... granulomatosis - microscopic ... - systemic ... Vessels #Diagnosis #Rheumatology
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
c-ANCA - Vasculitis ... granulomatosis p-ANCA ... - Vasculitis, e.g ... Microscopic polyangiitis ... diagnosis #table #rheumatology
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
polyangiitis, Microscopic ... vasculitis, Behcet ... Immune Complex: Systemic ... Rheumatoid arthritis, Systemic ... testing: anti-ANCA
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Diagnosis: • Systemic ... Presentation: Systemic ... purpura: Strong sign ... )): Microscopic ... Differential #Diagnosis #Rheumatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Using fluorescence microscopy ... Disease! ... • Homogeneous: Systemic ... ) • Speckled: Systemic ... #patterns #rheumatology
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
Non-Infectious Aortitis: • Vasculitides ... Nodosa (PAN), ANCA ... associated vasculitis ... Arthritis (RA), Systemic ... Differential #Diagnosis #rheumatology
Vasculitis Involving the Skin - Differential Diagnosis Framework Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis Secondary: CTD: SLE, RA
Vasculitis Involving ... • ANCA Associated ... : - Microscopic ... : • Behcet Disease ... #dermatology #rheumatology
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