11 results
Medications causing Acute Kidney Injury (AKI)
Prerenal:
 • Dehydration: Diuretics
 • Altered intrarenal autoregulation: ACEIs / ARBs,
Medications causing Acute ... tenofovir • AIN: Beta-lactams ... sphincter tone: • Opiates ... #pharmacology # ... differential #diagnosis
Primary Dermatologic Nail Disorders - Differential Diagnosis Algorithm
Nail Plate - Pitting
 • Psoriasis
 • Alopecia Areata
Nail
Primary Dermatologic ... Nail Disorders - Differential ... Diagnosis Algorithm ... Under Nails • Drug-Induced ... Trauma/lnfection - Acute
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Diagnosis Framework ... Defects: Sickle cell anemia ... Haptoglobin ↓ - Lactate ... #Diagnosis #hematology
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework

LDH is a cytoplasmic enzyme present in tissues throughout
Elevated Lactate ... Dehydrogenase (LDH) - Differential ... Diagnosis Framework ... hepatitis • Acute ... Idiosyncratic LDH Elevation
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
Acidosis - Differential ... circulation If drugs ... peritonitis - Acute ... 30mmHg) - Severe anemia ... #Differential #
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm
Extravascular - Spleen and RES-mediated hemolysis
 -
Diagnosis Algorithm ... immune-complex hemolytic anemia ... • Acute HTR ... #Diagnosis #Algorithm ... #Causes #Hematology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor
The maturation factor is
suppression (e.g. drugs ... Index > 3: • Acute ... Production #Index #hematology ... #anemia #differential ... #diagnosis #calculation
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... infection) - Drugs ... (Beta lactam antibiotics ... Extravascular #Causes #differential ... #diagnosis #hematology
Creatine Kinase - Causes of Elevated CK Levels
Acute CK Elevation (Pain > Weakness):
 • RHABDOMYOLYSIS
Elevated CK Levels Acute ... CK Elevation (Pain ... RHABDOMYOLYSIS - Drugs ... #Elevated #CK #differential ... #diagnosis #rhabdomyolysis
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
result in severe anemia ... Mild-to-moderate elevation ... Serum lactate ... WBC count and differential ... #Workup #Hematology