11 results
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Diagnosis Framework ... Defects: Sickle cell anemia ... Hypophostphatemia Laboratory ... Haptoglobin ↓ - Lactate ... #Diagnosis #hematology
Medications causing Acute Kidney Injury (AKI)
Prerenal:
 • Dehydration: Diuretics
 • Altered intrarenal autoregulation: ACEIs / ARBs,
Medications causing Acute ... tenofovir • AIN: Beta-lactams ... sphincter tone: • Opiates ... #pharmacology # ... differential #diagnosis
Primary Dermatologic Nail Disorders - Differential Diagnosis Algorithm
Nail Plate - Pitting
 • Psoriasis
 • Alopecia Areata
Nail
Primary Dermatologic ... Nail Disorders - Differential ... Diagnosis Algorithm ... Under Nails • Drug-Induced ... Trauma/lnfection - Acute
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework

LDH is a cytoplasmic enzyme present in tissues throughout
Elevated Lactate ... Dehydrogenase (LDH) - Differential ... Diagnosis Framework ... hepatitis • Acute ... #diagnosis #Laboratory
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
Lactic Acidosis - Differential ... circulation If drugs ... - assess other laboratory ... peritonitis - Acute ... 30mmHg) - Severe anemia
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm
Extravascular - Spleen and RES-mediated hemolysis
 -
Diagnosis Algorithm ... immune-complex hemolytic anemia ... • Acute HTR ... #Diagnosis #Algorithm ... #Causes #Hematology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor
The maturation factor is
suppression (e.g. drugs ... Index > 3: • Acute ... Production #Index #hematology ... #anemia #differential ... #diagnosis #calculation
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... infection) - Drugs ... (Beta lactam antibiotics ... Extravascular #Causes #differential ... #diagnosis #hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
TTP - Laboratory ... result in severe anemia ... elevation Serum lactate ... WBC count and differential ... #Workup #Hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Diagnosis Framework ... - Hemolytic anemia ... - APLS • Acute ... #Diagnosis #hematology