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differential causes nephrology management acute high hyperkalemia rhabdomyolysis treatment algorithm hypertension injury kidney kidneyinjury medications secondary summary toxicology vancomycin
Medications causing Acute Kidney Injury (AKI) Prerenal: • Dehydration: Diuretics • Altered intrarenal autoregulation: ACEIs / ARBs,
sphincter tone: • Opiates ... decongestants) • Any drug ... #Medications #Drugs ... #pharmacology # ... differential #diagnosis
Common causes of Acute Kidney Injury AKI - Differential Diagnosis HEMODYNAMIC • Cardiac failure: Impaired forward flow,
Kidney Injury AKI ... systemic disease or drugs ... hypotension • Drugs ... Nephritis (AIN) • Drugs ... #nephrology
Vancomycin Associated Acute Kidney Injury • Drug induced acute kidney injury is generally defined as a
Kidney Injury • Drug ... 24-72 hours of drug ... #Vancomycin #AKI ... #pharmacology # ... toxicology #diagnosis
Secondary Causes of Hypertension - Differential Diagnosis Algorithm Hypertension - BP > 140/90 (>130/80 for DM) Hypertensive urgency
Consider secondary HTN ... hypertension (multi-drug ... resistance) Renal ... Nephritic syndrome • AKI ... #Secondary #Nephrology
Rhabdomyolysis - Differential Diagnosis and Management Summary Trauma: • Immobilization, Crush iniury, Compartment syndrome, Electrical injury Exertional: •
- Differential Diagnosis ... Drugs (Statins), ... Dermatomyositis) AKI ... Monitor potassium ... hyperkalemia or ATN
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
- Differential Diagnosis ... transfusion • HTN ... reactions Common Drugs ... #causes #potassium ... #high #nephrology
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
- Differential Diagnosis ... transfusion • HTN ... reactions Common Drugs ... • Recent IV potassium ... #high #nephrology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
- Differential Diagnosis ... - Toxins - Drugs ... + myoglobin AKI ... Monitor potassium ... hyperkalemia or ATN
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