7 results
Drug-Induced Acute Kidney Injury - Sites of Action Along the Nephron

#DrugInduced #AcuteKidneyInjury #AKI #Nephrology #Pathophysiology #Pharmacology
Drug-Induced Acute ... Kidney Injury - ... #DrugInduced #AcuteKidneyInjury ... AKI #Nephrology #Pathophysiology ... #Pharmacology
Medications causing Acute Kidney Injury (AKI)
Prerenal:
 • Dehydration: Diuretics
 • Altered intrarenal autoregulation: ACEIs / ARBs,
causing Acute Kidney ... sphincter tone: • Opiates ... #Medications #Drugs ... #pharmacology # ... differential #diagnosis
Drug-Induced Edema
Drug-induced edema is caused by many drugs & can coincide with or worsen pre-existing peripheral
Drug-Induced Edema ... Drug-induced edema ... Medication #Causes #Differential ... #Pharmacology # ... Pathophysiology
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
Mechanisms of Drug-Induced ... #hyperkalemia #differential ... #diagnosis #pathophysiology ... #pharmacology #
Uric Acid Homeostasis
In the liver, purines are metabolized to uric acid. The last step in purine
The gout drug pegloticase ... produced The kidneys ... Homeostasis #Gout #Pathophysiology ... #Pharmacology #
Numerous drugs taken by elderly persons can affect water balance by direct action on the kidney
Numerous drugs taken ... action on the kidney ... action on the kidney ... #Diagnosis #Pharmacology ... DrugInduced #List #Differential
Allopurinol Pharmacology Summary

Xanthine oxidase inhibitor blocking the formation of new uric acid
Initiate 1-2 days prior to
Allopurinol Pharmacology ... hypersensitivity Drug ... metabolites in the kidney ... #Allopurinol #Pharmacology ... #pathophysiology