8 results
Pathophysiology of the Renin-angiotensin-aldosterone system (RAAS) and inhibitors

#Pathophysiology #Pharmacology #RAAS #Renin #Angiotensin #Aldosterone #System #ACEInhibitors
Pathophysiology ... of the Renin-angiotensin-aldosterone ... #Pharmacology # ... RAAS #Renin #Angiotensin ... #Aldosterone #System
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
Mechanisms of Drug-Induced ... Lisinopril) • Angiotensin ... differential #diagnosis #pathophysiology ... #pharmacology # ... potassium #medications
Here’s a review of the Renin-Angiotensin-Aldosterone system (RAAS)

This is a very common pathway that clinicians should
review of the Renin-Angiotensin-Aldosterone ... RAAS inhibiting drug ... RAAS inhibiting drugs ... ReninAngiotensinAldosteroneSystem #RAAS #Pharmacology ... #Renin #Angiotensin
Drugs that Impair Renal Potassium Excretion 

Decreased ENaC channel function: Amiloride, Triamterene, Pentamidine
Decreased Aldosterone Synthesis: Heparin,
Drugs that Impair ... Renal Potassium ... #Hyperkalemia #Pathophysiology ... #Pharmacology # ... Impaired #Potassium
Sites of Action of Drugs that Interfere with the Renin-Angiotensin-Aldosterone system

#ReninAngiotensinAldosterone #RAAS #System #Pharmacology #Targets #Sites
Sites of Action of Drugs ... with the Renin-Angiotensin-Aldosterone ... #RAAS #System #Pharmacology
Causes of Hyperkalemia
Pseudohyperkalemia
 - Tourniquet use
 - Hemolysis (in vitro)
 - Leukocytosis
 - Thrombocytosis
Intra- to extracellular
drugs - Transfusion ... Renal failure* - Drugspotassium-sparing ... , angiotensin-converting ... enzyme inhibitors, angiotensin ... tacrolimus - Aldosterone
Angiotensin Receptor Blockers 
Recommended Dose Conversions 

Valsartan 
Irbesartan 
Losartan 
Olmesartan 
Telmisartan 
Candesartan 
Azilsartan 
Eprosartan 

A few
Angiotensin Receptor ... dose of another drug ... recalls, this drug ... for increased potassium ... Table #Dosing #Pharmacology
Causes of Hyperkalemia
l. Pseudohyperkalemia
  A Cellular efflux; thrombocytosis, erythrocytosis, leukocytosis, in vitro hemolysis
  B.
Inhibition of the renin-angiotensin-aldosterone ... Drugs: nonsteroidal ... Drug-associated: ... adrenal hyperplasia, aldosterone ... Diagnosis #High #Potassium