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differential causes medications hyperkalemia management treatment acute aki aldosterone arb blockers channelblockers classification conversion dose dosing druginduced dysgeusia high hygiene
Mechanisms of Drug-Induced Hyperkalemia • Direct renin inhibitor (Aliskiren) • Renin release inhibition (NSAIDs, Beta-Blockers)
Mechanisms of Drug-Induced ... #differential #diagnosis ... #pathophysiology ... #pharmacology # ... potassium #medications
Here’s a review of the Renin-Angiotensin-Aldosterone system (RAAS) This is a very common pathway that clinicians should
review of the Renin-Angiotensin-Aldosterone ... RAAS inhibiting drug ... RAAS inhibiting drugs ... ReninAngiotensinAldosteroneSystem #RAAS #Pharmacology ... #Renin #Angiotensin
Drugs that Impair Renal Potassium Excretion Decreased ENaC channel function: Amiloride, Triamterene, Pentamidine Decreased Aldosterone Synthesis: Heparin,
Drugs that Impair ... Renal Potassium ... #Hyperkalemia #Pathophysiology ... #Pharmacology # ... Impaired #Potassium
Potassium Channel Blockers - Medications 1. Cardiovascular Drugs 2. Psychiatric drugs 3. Other drugs 4. Synthetic opioids: Levomethadyl 5. Opium
Potassium Channel ... Other drugs 4. ... Organophosphates #Potassium ... #Differential #Diagnosis ... #Pharmacology #
Angiotensin Receptor Blockers Recommended Dose Conversions Valsartan Irbesartan Losartan Olmesartan Telmisartan Candesartan Azilsartan Eprosartan A few
Angiotensin Receptor ... dose of another drug ... recalls, this drug ... for increased potassium ... Table #Dosing #Pharmacology
Medications causing Acute Kidney Injury (AKI) Prerenal: • Dehydration: Diuretics • Altered intrarenal autoregulation: ACEIs / ARBs,
sphincter tone: • Opiates ... decongestants) • Any drug ... #Medications #Drugs ... #pharmacology # ... differential #diagnosis
Causes of Hyperkalemia Pseudohyperkalemia - Tourniquet use - Hemolysis (in vitro) - Leukocytosis - Thrombocytosis Intra- to extracellular
drugs - Transfusion ... Renal failure* - Drugs—potassium-sparing ... , angiotensin-converting ... enzyme inhibitors, angiotensin ... Hyperkalemia #Causes #diagnosis
Causes of Hypomagnesemia Redistribution: - IV glucose - Correction of diabetic ketoacidosis - IV hyperalimentation - Refeeding
osmotic diuresis - Potassium ... renal disease Drugs ... Hypomagnesemia #Causes #diagnosis ... #medications #drugs ... #pharmacology #
Rhabdomyolysis - Differential Diagnosis and Management Summary Trauma: • Immobilization, Crush iniury, Compartment syndrome, Electrical injury Exertional: •
- Differential Diagnosis ... Drugs (Statins), ... Dermatomyositis) AKI - Pathophysiology ... Monitor potassium ... #Differential #Diagnosis
Causes of Hyperkalemia l. Pseudohyperkalemia A Cellular efflux; thrombocytosis, erythrocytosis, leukocytosis, in vitro hemolysis B.
Drugs: nonsteroidal ... anti-inflammatory drugs ... Drug-associated: ... #Differential #Diagnosis ... #High #Potassium
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