9 results
Drugs that Impair Renal Potassium Excretion 

Decreased ENaC channel function: Amiloride, Triamterene, Pentamidine
Decreased Aldosterone Synthesis: Heparin,
Drugs that Impair ... Renal Potassium ... #Hyperkalemia #Pathophysiology ... #Pharmacology # ... Impaired #Potassium
Antiarrhythmics Pharmacology Summary
Cardiac Conduction Phases:
Phase 0 - Ventricular Depolarization:
 • Na+ channels open leading to a
Antiarrhythmics Pharmacology ... efflux increases out ... repolarization CLASS 3 - Potassium ... Antiarrhythmics #Pharmacology ... Classification #Classes #pathophysiology
Digoxin Pharmacology and Pathophysiology
1) Na/K ATPase Pump - Digoxin works by directly binding to and inhibiting
Digoxin Pharmacology ... and Pathophysiology ... rate (lengthens phase ... 4 and phase O of ... #Pathophysiology
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
Mechanisms of Drug-Induced ... differential #diagnosis #pathophysiology ... #pharmacology # ... potassium #medications
*Coronavirus Update*: investigational remdesivir for the treatment of COVID-19. Here is a quick highlight of two
*Coronavirus Update ... highlight of two Phase ... investigational new drug ... information check out
Uric Acid Homeostasis
In the liver, purines are metabolized to uric acid. The last step in purine
The gout drug pegloticase ... #Homeostasis #Gout ... #Pathophysiology ... #Pharmacology #
Antiarrhythmics - Vaughan Williams Classification:
CLASS 1 - Sodium Channel Blockers:
 • MOA: Block fast Na+ channels
• ↓ slope of phase ... • ↓ slope of phase ... repolarization CLASS 3 - Potassium ... Vaughan #Williams #Pharmacology ... Classification #Classes #pathophysiology
Nail Pathologies - Findings in or Near Nails

Paronychia 

A superficial infection of the proximal and lateral
to the nail plate ... photosensitive drug ... grow slowly out ... the nail grows out ... depressions of the nail plates
Allopurinol Pharmacology Summary

Xanthine oxidase inhibitor blocking the formation of new uric acid
Initiate 1-2 days prior to
Allopurinol Pharmacology ... hypersensitivity Drug ... #Allopurinol #Pharmacology ... #pathophysiology ... #gout #uricacid