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Back to the "10 Need to Know" series - Drug Therapeutic Target Levels. 

For lithium, target
Therapeutic Target Levels ... lithium, target levels ... vary depending on treatment ... mortality at a higher level
Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
function below injury level ... Sensory loss below level ... light touch below level ... motor function, level ... and #Acute #SpinalCord
Spinal Cord Injury by Nerve Root Levels
Spinal Root	Sensory	Motor	Reflex
C4	Acromioclavicular Joint	Respiration	None
C5	Radial Antecubital Fossa	Elbow Flexion	Biceps Reflex
C6	Dorsal Thumb	Wrist Extension	Brachioradialis Reflex
C7	Dorsal
by Nerve Root Levels ... Sphincter None #SpinalCord ... Injury #NerveRoots #Levels
Incomplete Spinal Cord Syndromes
Anterior Cord Syndrome:
 • Bilateral loss of motor, pain and temperature sensation below
sensation below level ... #Incomplete #SpinalCord
Diagnosis Adrenal Insufficiency - Algorithm

Step 1) Screening Test: 6-8AM Cortisol Level
 - Early morning cortisol levels
6-8AM Cortisol Level ... morning cortisol levels ... - Levels > 15 ... - Intermediate levels ... Peak cortisol level
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
Pain reported at level ... B12 and copper levels ... loss: Sensory level ... (1-5 levels below ... #spinal #cord #spinalcord
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
with higher CK levels ... , greater level ... after 2 years of treatment
Incomplete spinal cord syndromes (ISCS)
 • Central - Small Lesion - Suspended sensory deficit, classic cape
LMN deficit at level ... sensory deficits at level ... ISCS #Incomplete #spinalcord
Hypocalcemia is an electrolyte imbalance and is indicated by a low level of calcium in the
indicated by a low level ... blood calcium levels
Carbon Monoxide Poisoning

Symptoms are non-specific:
 - Headache 90%
 - Nausea/vomiting 50%
 - Vertigo 50%
 - Altered
Alarm (for CO levels ... measuring COHb levels ... Treatment: 100%