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Thrombocytosis - Differential Diagnosis Platelet Count > 450 Reactive: • Anemia/blood loss (Fe deficiency) • Infection/Sepsis • Non-infectious
Thrombocytosis - Differential ... trauma) • Post-splenectomy ... Thrombocytosis #Differential
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Thrombocytosis - Differential ... Other: • Post-splenectomy ... Thrombocytosis #Differential
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Thrombocytosis - Differential ... sarcoidosis) • Post-splenectomy ... Thrombocytosis #Differential
Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
• Blood smear: Differential ... Rituximab +++ 3 - Splenectomy
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
phenotype, Post-splenectomy ... Hemoglobinopathies, Post-splenectomy ... RBC #Morphology #differential
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Platelet Count - Differential ... Asplenia/post-splenectomy ... Thrombocytosis #Platelets #Differential
Reactive or "Atypical" Lymphocytosis Infection • Viral: EBV, CMV, HIV, Herpes viruses, Influenza, Varicella, HTLV-I • Bacterial:
Trauma • Post splenectomy ... Lymphocytosis #differential
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
intoxication, Post-splenectomy ... key #diagnosis #differential
Post-splenectomy blood smear demonstrating Howell-Jolly bodies and target cells. #Clinical #Pathology #BloodSmear #HowellJollyBodies #TargetCells #Splenectomy #Asplenic
Post-splenectomy ... #TargetCells #Splenectomy
Recommended Vaccinations for Asplenic Patients - Before and After Splenectomy #Management #Asplenic #Asplenia #Vaccinations #PrimaryCare #Vaccines #Splenectomy
Before and After Splenectomy ... PrimaryCare #Vaccines #Splenectomy
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