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diagnosis lupus antiphospholipid disease erythematosus eular2019 hemeonc hemophagocytic hlh lymphohistiocytosis summary systemic thrombocytopenia activation apml behcet calcium cerebritis cns cppd
2019 EULAR recommendations for thrombosis in (Antiphospholipid Syndrome) APS Venous Thrombosis - Arterial Thrombosis INR Target Duration Recurrence Dr. Laurent ARNAUD
Antiphospholipid Syndrome ... #APS #management ... #EULAR2019 #guidelines ... #rheumatology # ... hematology #treatment
2019 EULAR Recommendations - Obstetrics Management in (Antiphospholipid Syndrome) APS Previous Thrombosis? Previous Pregnancy Complications? Dr. Laurent ARNAUD @Lupusreference #obstetrics
) APS Previous ... #APS #management ... #EULAR2019 #guidelines ... #rheumatology # ... obgyn #treatment
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Disease, PRES Pathophysiology ... (for secondary APS ... CNS #neurology #rheumatology ... cerebritis #diagnosis #management
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
block • Sjogren syndrome ... severe disease Treatment ... Hydroxychloroquine *Short ... Summary #diagnosis #rheumatology ... #management
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... : - Neuro: AMS ... : • Pathophysiology ... TLS #diagnosis #management ... #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Pathophysiology ... APML #diagnosis #management ... #hematology #oncology
Management of Lupus Nephritis Lupus nephritis (LN) in 10 to 40% of SLE Hallmark = proteinuria 20.5 g/g
Management of Lupus ... in 10 to 40% of SLE ... severity (ISN/RPS ... #treatment #management ... #rheumatology #
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
cytokines, such as ... erythematosus [SLE ... Treatment: • Corticosteroids ... #Diagnosis #Management ... #Hematology #Rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Oral aphthae : SLE ... • Arthritis: SLE ... Treatment: • Oral ... #diagnosis #management ... signs #symptoms #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... Autoimmune diseases: SLE ... Lymphohistiocytosis #diagnosis #management ... #treatment #summary ... #rheumatology
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