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diagnosis treatment oncology syndrome comparison lupus nephrology neurology signs sle symptoms table abscess aflp anemia aplastic apml arteritis bandemia bone
Causes of Bone/Joint Pain in Sickle Cell Disease Vaso-occlusive pain: • Mechanism: ischemic pain • Can present
Causes of Bone/Joint ... dx and stage ... • Differentiate ... #diagnosis #causes ... #hematology
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
Risk factors: Critical ... blood donor • Pathophysiology ... without other cause ... fluid balance, and CXR ... Transfusion #Reactions #hematology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... , dyspnea, +/- CXR ... TLS #diagnosis #management ... #hematology
Lung Abscess - Diagnosis and Management Summary Lung Abscess Etiology: • Necrosis of lung parenchyma by a
• Most common cause ... Lung Abscess Pathophysiology ... Lung Abscess - Clinical ... Blood cultures • CXR ... #causes #management
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... = nonspecific (nausea ... AP, ↑INR, ↑BUN/Cr ... infiltration) Differential ... #pathophysiology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... ↑ sIL-2R >2400 Ul ... Drugs, Unknown cause ... Lymphohistiocytosis #diagnosis #management ... treatment #summary #rheumatology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
ATRA treatment Pathophysiology ... common • Imaging: CXR ... initiation • Differential ... APML #diagnosis #management ... #hematology #oncology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Disease, PRES Pathophysiology ... autoantibodies that will cause ... CNS #neurology #rheumatology ... cerebritis #diagnosis #management
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook Presentation: • Plts ↓50% (nadir
♀, ↑Age, ESRD Pathophysiology ... hypercoagulable state ... Diagnosis: • Clinical ... non-heparin A/C if clinical ... #Treatment #Hematology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... Discontinuation of causal ... 40, F:M 9:1 • Clinical ... #rheumatology # ... diagnosis #management
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