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diagnosis management differential oncology classification comparison disorders table aplastic arteritis cancer chronic cll druginduced eosinophil eosinophilia essential et extravascular gca
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... Differential Diagnosis Algorithm ... effect following treatment ... Iron deficiency anemia ... #Causes #Hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Causes of Extravascular ... Differential Diagnosis Algorithm ... Sickle cell • Unstable ... immune-complex hemolytic anemia ... #Causes #Hematology
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Disorders Testing Algorithm ... workup for specific symptoms ... for secondary causes ... glucocorticoid treatment ... Differential #diagnosis #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
cytometry → >500/uL ... of anemia or thrombocytopenia ... Constitutional symptoms ... marrow failure with anemia ... Leukemia #oncology #hematology
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
without other cause ... ARDS to explain symptoms ... : 33% • Treatment ... : No • Treatment ... Transfusion #Reactions #hematology
Hematology Algorithms Anemia is described as a reduction in the proportion of the red blood cells.
Hematology Algorithms ... Anemia is described ... experience some symptoms ... Pancytopenia is a hematologic ... These causes could
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... Dehydration • Symptoms ... Lysis Syndrome: • Pathophysiology ... diagnosis #management #hematology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Differential Diagnosis Algorithm ... pattern of spread, B symptoms ... Responsive to Treatment ... Classification #pathophysiology ... #Hematology #Diagnosis
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
and petechiae Causes ... Treatment: ... • Improve the symptoms ... years who have a suitable ... #oncology #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... ↑ sIL-2R >2400 Ul ... Treatment: • ... diagnosis #management #treatment ... #summary #rheumatology
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