12 results
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... Clinical triad: Fever ... #AdultOnset #Stills ... Disease #diagnosis #management ... #treatment #rheumatology
Adult-Onset Still's Disease (AOSD)
Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
Adult-Onset Still's ... : High spiking fever ... #AdultOnset #Stills ... Disease #AOSD #rheumatology ... #diagnosis #management
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
Adult Onset Still's ... - Fever spikes ... #Adult #onset #Stills ... AOSD #diagnosis #rheumatology ... #management
Hantavirus
Pathogen: Hantavirus - Rodents are the primary reservoir
Transmission:
 • Shed in the urine, feces, saliva of
• Prodrome: fever ... , chills, myalgias ... Hantavirus #diagnosis #management ... #treatment #microbiology
Disseminated Gonococcal Infection - Diagnosis and Management Summary

Bacteremic spread of the Gram-negative diplococci Neisseria gonorrhoeae. History
Diagnosis and Management ... syndrome: • Fever ... , chills, generalized ... gonorrhea #Diagnosis #Management ... #Microbiology #
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
• Adult-onset Still ... disease • Periodic fever ... - Nonremitting fever ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Capnocytophaga
Pathogen: Capnocytophaga
 • 9 species, C. canimorsus responsible for the majority of infections
 • Gram-negative rod,
• Cellulitis: Fever ... , Chills, General ... Capnocytophaga #canimorsus #microbiology ... infectiousdiseases #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
activation and cytokine storm ... following: • Fever ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
• Clinical: fever ... +, Adult-onset Still ... Lymphohistiocytosis #diagnosis #management ... treatment #summary #rheumatology
Endocarditis Summary

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV substance use
• IV catheter
• Recent
Hypercoagulable (APLAS) Microbiology ... Generalized: • Chills ... night sweats, fever ... Persistent bacteremia/fevers ... Endocarditis #diagnosis #management