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diagnosis rheumatology differential lupus management dermatology erythematosus systemic antibodies ana antinuclear causes classification signs symptoms syndrome table workup autoantibodies diseases
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
in drug-induced SLE ... Vasculitis: • ... Polyangiitis (Churg-Strauss ... Renal-limited vasculitis ... antibodies #diagnosis #rheumatology
Classification of Vasculitis Vasculitis of large vessels - Arteritis temporalis (giant-cell arteritis) - Takayasu
large vessels - Arteritis ... - Takayasu arteritis ... small vessels - ANCA-associated ... - Churg-Strauss ... Vessels #Diagnosis #Rheumatology
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
Non-Infectious Aortitis: • Vasculitides ... Nodosa (PAN), ANCA ... associated vasculitis ... erythematosus (SLE ... Differential #Diagnosis #rheumatology
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
- Drug-induced SLE ... c-ANCA - Vasculitis ... granulomatosis p-ANCA ... - Vasculitis, e.g ... diagnosis #table #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
and often causes arthritis ... Glomerulonephritis, arthritis ... Vasculitis: + MPO-ANCA ... , and SLE) • Urinalysis ... differential #diagnosis #rheumatology
Vasculitis Involving the Skin - Differential Diagnosis Framework Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis Secondary: CTD: SLE, RA
Secondary: CTD: SLE ... • ANCA Associated ... : • Temporal arteritis ... • Takayasu's arteritis ... : • Behcet Disease
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
IBD, Whipple's disease ... • Whipple's disease ... , Lyme disease, ... Vasculitis (e.g. ... differential #diagnosis #rheumatology
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
vasculitis (Eosinophilic ... vasculitis, Behcet ... erythematosus, Rheumatoid arthritis ... testing: anti-ANCA ... , biopsy By Tess
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Malar rash • SLE ... infection • Lyme disease ... Hypersensitivity vasculitis ... IBD • RA • SLE ... Antiphospholipid-antibody syndrome • Vasculitis
Causes of Diffuse Lung Disease. Collagen vascular - Scleroderma - Rheumatoid arthritis -
- Rheumatoid arthritis ... Dermatomyositis - SLE ... - Toxic gas Vasculitides ... granulomatosis - Churg-Strauss ... - Giant cell arteritis
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