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differential rheumatology dermatology management alopecia classification hairloss vasculitis arthritis diffuse disease druginduced erythematosus peds antibodies antibody antineutrophil antinuclear antiphospholipid aortitis
Algorithm for the Evaluation and Management of Sickle Cell Crises Clinical Manifestations and Management #Diagnosis #Management #Hematology #SickleCell
Evaluation and ... Management #Diagnosis ... #Management #Hematology ... Manifestations #Workup ... #Algorithm #Ddxof
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
(SLE) - Diagnosis ... • Immunologic Workup ... : - ANA > ... Positive in 60-80% of cases ... • Evolution:
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
• Immunologic Workup ... : - ANA > ... Discontinuation of causal ... : - ANA > ... #diagnosis #management
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
) • Systemic lupus ... in drug-induced SLE ... Polyangiitis (Churg-Strauss ... Jcortesizaguirr #ANA ... Antineutrophil #antibodies #diagnosis
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
Negative IF): • PR3-ANCA ... (C-ANCA): GPA > ... > eGPA • MPO-ANCA ... (P-ANCA): eGPA, ... #algorithm #rheumatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
and Workup History ... function test, ANA ... (e.g., SLE), anti-phospholipid ... - Bone marrow evaluation ... #Causes #Workup
Top 10 situations when to think about lupus 1) Inflammatory joint pain (especially in the wrists and
pericarditis (search ANA ... pleurisy (search ANA ... person (search ANA ... cytopenia (search ANA ... #diagnosis #sle
Serious Bacterial Illness (SBI): 1) UTI and pyelonephritis Most common cause of SBI Accounts for 3-8% of uncharacterized fevers Female
pyelonephritis Most common cause ... Consider BCx, CSF evaluation ... of respiratory distress ... suggested if: - ANC ... SeriousBacterialIllness #Ddxof
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
- Differential Diagnosis ... Nodosa (PAN), ANCA ... (RA), Systemic lupus ... erythematosus (SLE ... #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
often causes arthritis ... such as systemic lupus ... LFT • ESR • ANA ... SLE) • Urinalysis ... #rheumatology #
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