40 results
diagnosis hematology differential management algorithm anemia alopecia hairloss nutrition thrombocytosis chronic diffuse folate intravascular leukemia mds myelodysplastic purpura acquired anticoagulation
Diagnosing Vitamin B12 and/or Folate Deficiency It turns out that simply measuring serum levels of B12 or
and/or Folate Deficiency ... with low B12 stores ... normal tissue stores ... tissue folate stores ... Diagnosis #Nutrition #Hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... old, ~10,000 new cases ... only curative treatment ... Myelodysplastic #Syndrome ... #hematology #oncology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Causes of Thrombocytopenia ... • Folate Deficiency ... Non-lmmune: • HELLP Syndrome ... Diagnosis #Algorithm #Causes ... #Hematology
Etiologies of Folate Deficiency • Decreased dietary intake - uncommon in this era • Increased requirements
Etiologies of Folate Deficiency ... folate that can cause ... mobilize folate stores ... depleted tissue stores ... differential #diagnosis #hematology
Treatment of Thrombotic Thrombocytopenic Purpura (TTP) Diagnosis of TTP: • Rare and severe, ADAMTS13 deficiency • Autoimmune
Treatment of Thrombotic ... severe, ADAMTS13 deficiency ... PLEX and RTX • Short-term ... #rheumatology # ... hematology
Recurrent / Breakthrough DVT During Anticoagulation Subtherapeutic Anticoagulation Hypercoagulable State - Antithrombin deficiency - Hypercoagulability ot
- Antithrombin deficiency ... Structural - Pelvic masses ... - May-Thurner syndrome ... anticoagulation #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... Acute hemolysis, deficiency ... Rebound effect from treatment ... Kawasaki, Nephrotic syndrome ... Diagnosis #Algorithm #hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... effect following treatment ... malignancy • Iron deficiency ... Diagnosis #Algorithm #Causes ... #Hematology
Iron Deficiency Anemia (IDA) Tests: • MCV/RBC - RBC ↓ in proportion to the ↓ in hemoglobin
Iron Deficiency ... total body iron stores ... DharSaty #Iron #Deficiency ... Fe #diagnosis #hematology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Causes of Thrombocytosis ... specifically: iron deficiency ... Myelodysplastic syndrome ... Differential #Diagnosis #Causes ... #hematology #secondary
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