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diagnosis differential management anemia folate nutrition oncology algorithm alopecia aplastic coagulation comparison comparisontable dic disseminated fe ferritin folicacid hair hairloss
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... effect following treatment ... malignancy • Iron deficiency ... Diagnosis #Algorithm #Causes ... #Hematology
Treatment of Thrombotic Thrombocytopenic Purpura (TTP) Diagnosis of TTP: • Rare and severe, ADAMTS13 deficiency • Autoimmune
Treatment of Thrombotic ... severe, ADAMTS13 deficiency ... PLEX and RTX • Short-term ... #rheumatology # ... hematology
Diagnosing Vitamin B12 and/or Folate Deficiency It turns out that simply measuring serum levels of B12 or
and/or Folate Deficiency ... with low B12 stores ... normal tissue stores ... tissue folate stores ... Diagnosis #Nutrition #Hematology
Etiologies of Folate Deficiency • Decreased dietary intake - uncommon in this era • Increased requirements
Etiologies of Folate Deficiency ... folate that can cause ... mobilize folate stores ... depleted tissue stores ... differential #diagnosis #hematology
Iron Deficiency Anemia (IDA) Tests: • MCV/RBC - RBC ↓ in proportion to the ↓ in hemoglobin
Iron Deficiency ... total body iron stores ... DharSaty #Iron #Deficiency ... Fe #diagnosis #hematology
Allopecia - Differential Diagnosis Framework for Hair Loss Localized / Focal Hair Loss Pattern: • Scarring Alopecia:
Lithium • Stress ... Scaling, pustules, crusts ... texture at bald spots ... Major psychologic stress ... Differential #Diagnosis #dermatology
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
without other cause ... : 33% • Treatment ... of (Acute resp distress ... , and CXR with pulmonary ... Transfusion #Reactions #hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
thrombopoietin deficiency ... + Bleeding Treatment ... Treat primary cause ... #treatment #management ... #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
and petechiae Causes ... anemia, GATA2 deficiency ... , CTLA4 deficiency ... aplastic anemia Treatment ... Anemia #oncology #hematology
Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause -
Causes of Neutropenia ... the most common cause ... hypertension and/or drug treatment ... anemia-rare - Copper deficiency-rare ... #hematology
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