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Initial Clinical and Laboratory Data Base for Defining Major Syndromes in Nephrology

#Major #Syndromes #Nephrology #Diagnosis #Workup
Defining Major Syndromes ... in Nephrology ... #Major #Syndromes ... #Nephrology #Diagnosis ... #Table
Hypernatremia - Differential Diagnosis Workup Algorithm

1) Check Urine Osmolality:
 > 600 mOsm/kg - Implies extrarenal mechanism
Differential Diagnosis Workup ... Hypervolemic: Conn syndrome ... , Cushing syndrome ... #Algorithm #nephrology ... #sodium
Causes of Hyponatremia - Differential Diagnosis Algorithm
Hypovolemia, UNa > 20: 
 • Renal losses, Diuretic excess,
Cerebral salt wasting syndrome ... Hypothyroidism, Stress ... , Drugs, Syndrome ... • Nephrotic syndrome ... Algorithm #Causes #nephrology
Hypernatremia Classification and Features According to Volume Status
 - Hypervolemic hypernatremia - Cushing's syndrome, Primary hyperaldosteronism,
hypernatremia - Cushing's syndrome ... , Loop diuretics ... Postobstructive diuresis ... Diagnosis #Comparison #Table ... #Nephrology
Hypernatremia Diagnosis and Workup

Step 1 . Repeat the sodium concentration.
Step 2.  Check plasma osmolality.
NORMAL PLASMA
Diagnosis and Workup ... Repeat the sodium ... volume loss - diuretics ... • nephrotic syndrome ... #Algorithm #Nephrology
Mechanisms of nephron damage in cardiorenal syndrome
 • Increased renal interstitial pressure
 • Hypoperfusion
 • Reduced
in cardiorenal syndrome ... hypertrophy • Sodium ... activities • Diuretic ... #cardiorenal #syndrome ... pathophysiology #nephrology
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
disequilibrium syndrome ... and nephrotic syndrome ... and nephrotic syndrome ... disease • Liddle syndrome ... #Nephrology #Pharmacology
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
: SIADH, Renal Sodium ... loss (diuretics ... Cirrhosis, Nephrotic syndrome ... differential #diagnosis #table ... #sodium #nephrology
Hyponatremia - Differential Diagnosis Algorithm
Hypovolemic - Give volume
Hypervolemic (Edematous) - Look for and treat underlying cause
cirrhosis, nephrotic syndrome ... Stress, Nausea, ... Pulmonary Diseases ... Algorithm #diagnosis #nephrology ... #sodium
Causes of Hyponatremia - Differential Diagnosis Algorithm
Syndrome of Inappropriate ADH - Euvolemic; no physiologic stimulus to
Diagnosis Algorithm Syndrome ... Pain/Post-op • Neurologic ... • Drugs • Pulmonary ... • Nephrotic syndrome ... #Hyponatremia #Nephrology