38 results
Algorithm for Differentiating Gitelman syndrome from Bartter syndrome
 • Urine Chloride
 • Urine Ca/Cr ratio

Dr. Krithika
Differentiating Gitelman ... syndrome • Urine ... krithicism #Gitelman ... #Algorithm #nephrology ... #hypokalemia #diagnosis
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome ... Syndrome is a rare ... thiazide-sensitive sodium-chloride ... H+ secretion → Hypokalemia ... #nephrology #diagnosis
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
Gitelman Syndrome ... thiazide-sensitive sodium ... Rhabdomyolysis Treatment ... #Syndrome #diagnosis ... #nephrology #management
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Hypokalemia - Differential ... Diagnosis Algorithm ... , Gitelman syndrom ... #Differential #Diagnosis ... potassium #low #nephrology
Causes of HyperKalemia - Differential Diagnosis
Increased extracellular K+:
 • Tissue injury
 • Hemolysis
 • Rhabdomyolysis
 •
- Differential Diagnosis ... • Tumor lysis syndrome ... Elimination: • AKI ... blockers - MCW Nephrology ... #Differential #Diagnosis
Causes of Hyponatremia - Differential Diagnosis Algorithm
Syndrome of Inappropriate ADH - Euvolemic; no physiologic stimulus to
Pain/Post-op • Neurologic ... • Drugs • Pulmonary ... Malignancy True hypovolemia ... • Reduced GFR, AKI ... #Hyponatremia #Nephrology
Causes of Hyponatremia - Differential Diagnosis Algorithm
Syndrome of Inappropriate ADH - Euvolemic; no physiologic stimulus to
Pain/Post-op • Neurologic ... • Drugs • Pulmonary ... Malignancy True hypovolemia ... • Reduced GFR, AKI ... #Hyponatremia #Nephrology
Causes of Hypokalemia - Differential Diagnosis Algorithm
Defining the cause of hypokalemia starts by measuring urinary K
Causes of Hypokalemia ... - Differential Diagnosis ... , Gitelman's syndrome ... #differential #diagnosis ... algorithm #causes #nephrology
Hypomagnesemia - Differential Diagnosis
Renal Causes of Hypomagnesemia - Familial:
Bartter syndrome and Gitelman syndrome, Isolated recessive hypomagnesemia,
- Differential Diagnosis ... Familial: Bartter syndrome ... and Gitelman syndrome ... with secondary, hypocalcemia ... #causes #nephrology
Gitelman Syndrome - Management
Treatment includes
 - Electrolyte replacement - K & Mg, preferably Cl salts
Gitelman Syndrome ... - Management Treatment ... In persistent hypokalemia ... #Syndrome #Management ... #Treatment #nephrology